Septin5 Phenotype Annotations

Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Septin5
septin 5
MGI:1195461

20 phenotypes from 3 alleles in 5 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Septin5^{tm1b(EUCOMM)Hmgu}/Septin5⁺ C57BL/6N-Septin5^{tm1b(EUCOMM)Hmgu}/Rbrc	abnormal bone structure	J:211773
	decreased body length	J:211773
	decreased bone mineral content	J:211773
	decreased bone mineral density	J:211773
	improved glucose tolerance	J:211773
	short tibia	J:211773
	small spleen	J:211773
	thrombocytopenia	J:211773
Septin5^{tm1b(EUCOMM)Hmgu}/Septin5^{tm1b(EUCOMM)Hmgu} C57BL/6N-Septin5^{tm1b(EUCOMM)Hmgu}/Rbrc	preweaning lethality, incomplete penetrance	J:211773
Septin5^tm1Bld/Septin5⁺ B6.Cg-Tyr^c-Brd Septin5^tm1Bld	normal nervous system phenotype	J:110101
Septin5^tm1Bld/Septin5^tm1Bld involves: 129S7/SvEvBrd	normal cardiovascular system phenotype	J:67409
Septin5^tm1Wtr/Septin5^tm1Wtr involves: 129S1/Sv * 129X1/SvJ	abnormal platelet physiology	J:109519
	normal hematopoietic system phenotype	J:109519
	increased platelet aggregation	J:109519
Septin5^tm1Wtr/Septin5^tm1Wtr involves: 129S1/Sv * 129X1/SvJ * CD-1	abnormal social/conspecific interaction behavior	J:147200
	abnormal spatial learning	J:147200
	normal behavior/neurological phenotype	J:147200
	decreased anxiety-related response	J:147200
	increased prepulse inhibition	J:147200
	increased startle reflex	J:147200
	normal nervous system phenotype	J:84539

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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