Cbx4 Phenotype Annotations

Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Cbx4
chromobox 4
MGI:1195985

14 phenotypes from 3 alleles in 3 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Cbx4^{tm1.1(KOMP)Vlcg}/Cbx4⁺ C57BL/6N-Cbx4^{tm1.1(KOMP)Vlcg}/Tcp	abnormal embryo size	J:211773
	decreased lean body mass	J:211773
	hyperactivity	J:211773
	increased total body fat amount	J:211773
Cbx4^{tm1.1(KOMP)Vlcg}/Cbx4^{tm1.1(KOMP)Vlcg} C57BL/6N-Cbx4^{tm1.1(KOMP)Vlcg}/Tcp	abnormal embryo size	J:211773
	preweaning lethality, complete penetrance	J:211773
Cbx4^tm1.1Gxu/Cbx4^tm1.1Gxu Tg(Lck-cre)#Zhu/0 involves: 129S2/SvPas * C57BL/6 * SJL/J	normal hematopoietic system phenotype	J:194053
Cbx4^tm1.1Gxu/Cbx4^tm1.2Gxu Tg(Foxn1-cre)1Tbo/0 involves: 129S2/SvPas * C57BL/6J	abnormal lymphopoiesis	J:194053
	abnormal thymus development	J:194053
	abnormal thymus physiology	J:194053
	decreased double-positive T cell number	J:194053
	decreased T cell number	J:194053
	thymus atrophy	J:194053
	thymus hypoplasia	J:194053
Cbx4^tm1.2Gxu/Cbx4^tm1.2Gxu involves: 129S2/SvPas * C57BL/6J	abnormal thymus development	J:194053
	abnormal thymus physiology	J:194053
	normal hematopoietic system phenotype	J:194053
	neonatal lethality, complete penetrance	J:194053
	thymus hypoplasia	J:194053

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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