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Mammalian Phenotype Ontology Annotations
Query Results - Summary
Symbol
Name
ID 		Pole
polymerase (DNA directed), epsilon
MGI:1196391
12 phenotypes from 2 alleles in 3 genetic backgrounds
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Allelic Composition
Genetic Background		 Annotated Term Reference
PoleTg(Tyr)2300A-1b1b1Ove/PoleTg(Tyr)2300A-1b1b1Ove
FVB/N-PoleTg(Tyr)2300A-1b1b1Ove 		embryonic lethality between implantation and placentation, complete penetrance J:175597
Poletm1.1Bdp/Poletm1.1Bdp
B6.129-Poletm1.1Bdp 		enlarged spleen J:153684
increased adenoma incidence J:153684
increased colon adenocarcinoma incidence J:153684
increased histiocytic sarcoma incidence J:153684
increased intestinal adenocarcinoma incidence J:153684
increased intestinal adenoma incidence J:153684
increased lung tumor incidence J:153684
increased lymphoma incidence J:153684
increased small intestine adenocarcinoma incidence J:153684
premature death J:153684
Poletm1.1Bdp/Poletm1.1Bdp
involves: 129S1/Sv * 129X1/SvJ * C57BL/6J 		increased tumor incidence J:153684
premature death J:153684
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
12/10/2024
MGI 6.24 		The Jackson Laboratory