Atp5if1 Phenotype Annotations

Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Atp5if1
ATP synthase inhibitory factor subunit 1
MGI:1196457

24 phenotypes from 3 alleles in 4 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Atp5if1^em1Jpy/Atp5if1^em1Jpy C57BL/6J-Atp5if1^em1Jpy	abnormal colon morphology	J:313048
	abnormal enterocyte morphology	J:313048
	abnormal mitochondrial matrix morphology	J:313048
	abnormal mitophagy	J:313048
	decreased energy expenditure	J:313048
	decreased enterocyte apoptosis	J:313048
	decreased locomotor activity	J:313048
	decreased mitochondrial size	J:313048
	decreased neutrophil cell number	J:312819
	decreased susceptibility to colitis induced morbidity/mortality	J:312819
	normal hematopoietic system phenotype	J:312819
	improved glucose tolerance	J:313048
	increased epididymal fat pad weight	J:313048
	increased liver weight	J:313048
	increased susceptibility to diet-induced obesity	J:313048
	insulin resistance	J:313048
Atp5if1^{tm1a(EUCOMM)Wtsi}/Atp5if1^{tm1a(EUCOMM)Wtsi} C57BL/6N-Atp5if1^{tm1a(EUCOMM)Wtsi}/Wtsi	decreased body weight	J:175295
	decreased circulating alanine transaminase level	J:175295
	decreased circulating alkaline phosphatase level	J:175295
	decreased total body fat amount	J:175295
Atp5if1^tm1Ksuj/Atp5if1^tm1Ksuj C57BL/6J-Atp5if1^tm1Ksuj	normal growth/size/body region phenotype	J:268424
	normal hematopoietic system phenotype	J:268424
	normal reproductive system phenotype	J:268424
Atp5if1^tm1Ksuj/Atp5if1^tm1Ksuj involves: C57BL/6J	abnormal cardiac muscle contractility	J:256558
Atp5if1^tm1Ksuj/Atp5if1^tm1Ksuj involves: C57BL/6J	decreased response of heart to induced stress	J:256558

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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