Hpn Phenotype Annotations

Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Hpn
hepsin
MGI:1196620

19 phenotypes from 3 alleles in 4 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Hpn^Hlb320/? C57BL/6J-Hpn^Hlb320/J	decreased circulating HDL cholesterol level	J:82961
Hpn^Hlb320/? C57BL/6J-Hpn^Hlb320/J	increased circulating cholesterol level	J:82961
Hpn^Hlb320/Hpn⁺ involves: C57BL/6J * C57L/J	decreased circulating cholesterol level	J:187708
	decreased circulating HDL cholesterol level	J:187708
	decreased circulating triglyceride level	J:187708
Hpn^Hlb320/Hpn^Hlb320 C57BL/6J-Hpn^Hlb320/J	decreased circulating cholesterol level	J:187708
	decreased circulating HDL cholesterol level	J:187708
	decreased circulating triglyceride level	J:187708
	impaired hearing	J:187708
	increased circulating alkaline phosphatase level	J:187708
Hpn^Hlb320/Hpn^Hlb320 involves: C57BL/6J * C57L/J	decreased body size	J:187708
	decreased circulating cholesterol level	J:187708
	decreased circulating HDL cholesterol level	J:187708
	decreased circulating triglyceride level	J:187708
Hpn^tm1Qwu/Hpn^tm1Qwu involves: 129X1/SvJ * NIH Swiss	abnormal auditory brainstem response waveform shape	J:123922
	abnormal cochlear ganglion morphology	J:123922
	abnormal cochlear inner hair cell physiology	J:123922
	abnormal cochlear outer hair cell physiology	J:123922
	abnormal myelination	J:123922
	abnormal tectorial membrane morphology	J:123922
	abnormal tectorial membrane striated-sheet matrix morphology	J:123922
	decreased activity of thyroid gland	J:123922
	decreased thyroxine level	J:123922
	enlarged tectorial membrane	J:123922
	impaired hearing	J:123922
	increased circulating alkaline phosphatase level	J:45393
	increased or absent threshold for auditory brainstem response	J:123922
Tg(Pbsn-Hpn,-GFP)DVv/0 involves: C57BL/6J * CBA	abnormal prostate gland morphology	J:92562

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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