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Mammalian Phenotype Ontology Annotations
Query Results - Summary
Symbol
Name
ID 		Birc3
baculoviral IAP repeat-containing 3
MGI:1197007
27 phenotypes from 2 alleles in 3 genetic backgrounds
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Allelic Composition
Genetic Background		 Annotated Term Reference
Birc3tm1Jda/Birc3tm1Jda
B6.Cg-Birc3tm1Jda 		abnormal gut-associated lymphoid tissue morphology J:166899
abnormal lymphocyte cell number J:166899
decreased B cell apoptosis J:166899
decreased follicular B cell number J:166899
decreased IgG1 level J:166899
decreased immature B cell number J:166899
enlarged mesenteric lymph nodes J:166899
increased B cell number J:166899
increased B cell proliferation J:166899
increased IgA level J:166899
increased IgG3 level J:166899
increased IgM level J:166899
increased marginal zone B cell number J:166899
increased T cell number J:166899
lymph node hyperplasia J:166899
Birc3tm1Jda/Birc3tm1Jda
involves: 129 * C57BL/6 		increased interferon-gamma secretion J:199221
increased T cell proliferation J:199221
Birc3tm1Rgk/Birc3tm1Rgk
B6.129X1-Birc3tm1Rgk 		abnormal cytokine secretion J:144012
abnormal immune cell physiology J:144012
abnormal interleukin-1 beta secretion J:144012
abnormal interleukin-12 secretion J:144012
abnormal leukocyte cell number J:144012
abnormal macrophage physiology J:144012
abnormal T cell physiology J:144012
abnormal tumor necrosis factor secretion J:144012
decreased macrophage cell number J:144012
decreased susceptibility to endotoxin shock J:144012
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
12/10/2024
MGI 6.24 		The Jackson Laboratory