Aebp1 Phenotype Annotations

Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Aebp1
AE binding protein 1
MGI:1197012

35 phenotypes from 4 alleles in 4 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Aebp1^{tm1.1(KOMP)Wtsi}/Aebp1⁺ C57BL/6N-Aebp1^{tm1.1(KOMP)Wtsi}/Tcp	decreased locomotor activity	J:211773
Aebp1^{tm1.1(KOMP)Wtsi}/Aebp1^{tm1.1(KOMP)Wtsi} C57BL/6N-Aebp1^{tm1.1(KOMP)Wtsi}/Tcp	abnormal tail morphology	J:211773
	preweaning lethality, complete penetrance	J:211773
Aebp1^tm1Hsro/Aebp1⁺ involves: 129S4/SvJae * C57BL/6J	decreased total body fat amount	J:125333
Aebp1^tm1Hsro/Aebp1^tm1Hsro involves: 129S4/SvJae * C57BL/6J	abnormal fat cell morphology	J:125333
	abnormal involution of the mammary gland	J:125333
	abnormal nursing	J:125333
	abnormal white adipose tissue morphology	J:125333
	decreased body weight	J:125333
	decreased circulating cholesterol level	J:125333
	decreased circulating triglyceride level	J:125333
	decreased susceptibility to diet-induced obesity	J:125333
	decreased total body fat amount	J:125333
	decreased white adipose tissue amount	J:125333
	postnatal growth retardation	J:125333
	prenatal lethality, incomplete penetrance	J:125333
Aebp1^tm1Mdl/Aebp1^tm1Mdl involves: 129S2/SvPas * C57BL/6	abnormal intestine morphology	J:70416
	abnormal liver morphology	J:70416
	curly tail	J:70416
	decreased cell proliferation	J:70416
	decreased survivor rate	J:70416
	herniated abdominal wall	J:70416
	impaired wound healing	J:70416
	kinked tail	J:70416
	perinatal lethality, incomplete penetrance	J:70416
	skin lesions	J:70416
Tg(Fabp4-Aebp1)1Hsro/? involves: FVB	abnormal fat cell morphology	J:125334
	atherosclerotic lesions	J:125334
	increased body weight	J:125334
	increased circulating insulin level	J:125334
	increased circulating leptin level	J:125334
	increased food intake	J:125334
	increased susceptibility to induced morbidity/mortality	J:125334
	increased susceptibility to weight gain	J:125334
	increased white adipose tissue amount	J:125334
	obese	J:125334
	premature death	J:125334

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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