Limk2 Phenotype Annotations

Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Limk2
LIM domain kinase 2
MGI:1197517

28 phenotypes from 4 alleles in 4 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Limk2^{Gt(OST80053)Lex}/Limk2^{Gt(OST80053)Lex} involves: 129S5/SvEvBrd * C57BL/6	abnormal cornea epithelium morphology	J:192231
	abnormal cornea morphology	J:192231
	abnormal eyelid development	J:192231
	decreased eye anterior chamber depth	J:192231
	eyelids open at birth	J:192231
	failure of eyelid fusion	J:192231
	increased incidence of corneal inflammation	J:192231
	retina neovascularization	J:192231
Limk2^tm1.1Tnak/Limk2^tm1.1Tnak either: (involves: 129S1/Sv * 129X1/SvJ * C57BL/6) or (involves: 129S1/Sv * 129X1/SvJ * CD-1)	abnormal kidney morphology	J:73966
	abnormal spermatocyte morphology	J:73966
	abnormal spermatogenesis	J:73966
	decreased renal glomerulus number	J:73966
	decreased testis weight	J:73966
	dilated renal tubule	J:73966
	increased male germ cell apoptosis	J:73966
	small seminiferous tubules	J:73966
Limk2^{tm1a(EUCOMM)Wtsi}/Limk2⁺ C57BL/6N-Limk2^{tm1a(EUCOMM)Wtsi}/Ics	abnormal locomotor activation	J:165965
	increased body weight	J:165965
	long tibia	J:165965
Limk2^whe/Limk2^whe B6.Cg-Lep^ob Limk2^whe/GrsrJ	normal adipose tissue phenotype	J:127016
	anterior iris synechia	J:127016
	cornea opacity	J:127016
	cornea vascularization	J:127016
	early eyelid opening	J:127016
	normal hearing/vestibular/ear phenotype	J:127016
	increased incidence of corneal inflammation	J:127016
	increased inner canthal distance	J:223062
	short mandible	J:127016
	normal skeleton phenotype	J:127016

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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