Irx3 Phenotype Annotations

Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Irx3
Iroquois related homeobox 3
MGI:1197522

19 phenotypes from 2 alleles in 3 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Irx3^em2(IMPC)H/Irx3^em2(IMPC)H C57BL/6N-Irx3^em2(IMPC)H/H	abnormal cornea morphology	J:211773
	abnormal snout morphology	J:211773
	decreased bone mineral content	J:211773
	decreased fasting circulating glucose level	J:211773
	increased grip strength	J:211773
Irx3^tm1Hui/Irx3^tm1Hui involves: 129S1/Sv * 129X1/SvJ	abnormal white adipose tissue physiology	J:208887
	decreased body weight	J:208887
	decreased fat cell size	J:208887
	decreased percent body fat/body weight	J:208887
	decreased susceptibility to diet-induced hepatic steatosis	J:208887
	decreased susceptibility to diet-induced obesity	J:208887
	improved glucose tolerance	J:208887
	increased energy expenditure	J:208887
	increased insulin sensitivity	J:208887
Irx3^tm1Hui/Irx3^tm1Hui involves: 129S1/Sv * 129X1/SvJ * C57BL/6	abnormal atrioventricular bundle conduction	J:175992
	abnormal heart electrocardiography waveform feature	J:175992
	abnormal QRS complex	J:175992
	abnormal R wave	J:175992
	prolonged QRS complex duration	J:175992

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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