Shox2 Phenotype Annotations

Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Shox2
SHOX homeobox 2
MGI:1201673

32 phenotypes from 7 alleles in 8 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Shox2^em1(IMPC)Bay/Shox2⁺ C57BL/6N-Shox2^em1(IMPC)Bay/Bay	abnormal retina blood vessel morphology	J:211773
Shox2^em1(IMPC)Bay/Shox2^em1(IMPC)Bay C57BL/6N-Shox2^em1(IMPC)Bay/Bay	prenatal lethality prior to heart atrial septation	J:211773
	preweaning lethality, complete penetrance	J:211773
Shox2^tm1.1Ddu/Shox2⁺ involves: 129S2/SvPas * C57BL/6J * SJL/J	normal limbs/digits/tail phenotype	J:107668
Shox2^tm1Acgg/Shox2^tm1Acgg involves: 129 * C57BL/6	abnormal heart development	J:135454
	abnormal sinus venosus morphology	J:135454
	embryonic lethality during organogenesis, complete penetrance	J:135454
	pericardial edema	J:135454
Shox2^tm1Ddu/Shox2^tm1.1Ddu Tg(Prrx1-cre)1Cjt/0 involves: 129S2/SvPas * C57BL/6J * SJL/J	abnormal cartilage development	J:107668
	abnormal forelimb stylopod morphology	J:107668
	abnormal hindlimb stylopod morphology	J:107668
	abnormal hindlimb zeugopod morphology	J:107668
	abnormal limb bone morphology	J:107668
	abnormal limb morphology	J:107668
	abnormal long bone epiphyseal plate morphology	J:107668
	absent femur	J:107668
	absent humerus	J:107668
	bowed tibia	J:107668
	normal mortality/aging	J:107668
	short limbs	J:107668
Shox2^tm1Ddu/Shox2^{tm3.1(cre)Ypc} involves: 129S2/SvPas * 129S6/SvEvTac * C57BL/6	embryonic lethality during organogenesis, incomplete penetrance	J:199319
	lethality throughout fetal growth and development, complete penetrance	J:199319
	sinoatrial node hypoplasia	J:199319
Shox2^tm1Ypc/Shox2^tm1Ypc involves: 129X1/SvJ	sinoatrial node hypoplasia	J:199319
Shox2^tm1Ypc/Shox2^tm1Ypc involves: 129X1/SvJ * C57BL/6	abnormal blood vessel morphology	J:101732
	abnormal heart morphology	J:101732
	abnormal palatal mesenchymal cell proliferation	J:101732
	abnormal palatal shelf fusion at midline	J:101732
	abnormal palatal shelf morphology	J:101732
	abnormal secondary palate development	J:101732
	anterior cleft palate	J:101732
	cleft secondary palate	J:101732
	embryonic lethality during organogenesis, incomplete penetrance	J:101732
Shox2^{tm3.1(cre)Ypc}/Shox2^tm4.1Ypc involves: 129S1/Sv * 129S6/SvEvTac * C57BL/6	embryonic lethality during organogenesis, incomplete penetrance	J:199319
	lethality throughout fetal growth and development, complete penetrance	J:199319
	sinoatrial node hypoplasia	J:199319
Shox2^tm4.1Ypc/Shox2^tm4.1Ypc involves: 129S6/SvEvTac * C57BL/6	embryonic lethality during organogenesis, incomplete penetrance	J:199319
	lethality throughout fetal growth and development, incomplete penetrance	J:199319

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