Cacna1g Phenotype Annotations

Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Cacna1g
calcium channel, voltage-dependent, T type, alpha 1G subunit
MGI:1201678

38 phenotypes from 7 alleles in 8 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Cacna1g^em1(IMPC)Mbp/Cacna1g^em1(IMPC)Mbp C57BL/6N-Cacna1g^em1(IMPC)Mbp/MbpMmucd	abnormal kidney morphology	J:211773
	abnormal skin morphology	J:211773
	abnormal spleen morphology	J:211773
	enlarged kidney	J:211773
	enlarged lymph nodes	J:211773
	enlarged testis	J:211773
	increased exploration in new environment	J:211773
Cacna1g^em1Ftan/Cacna1g⁺ C57BL/6NCrSlc-Cacna1g^em1Ftan	abnormal afterhyperpolarization	J:278129
	abnormal cerebellar cortex morphology	J:278129
	abnormal gait	J:278129
	ataxia	J:278129
	impaired coordination	J:278129
	neurodegeneration	J:278129
	Purkinje cell degeneration	J:278129
Cacna1g^em1Ftan/Cacna1g^em1Ftan C57BL/6NCrSlc-Cacna1g^em1Ftan	abnormal afterhyperpolarization	J:278129
	abnormal cerebellar cortex morphology	J:278129
	abnormal channel response	J:278129
	abnormal gait	J:278129
	abnormal neuron physiology	J:278129
	astrocytosis	J:278129
	ataxia	J:278129
	impaired coordination	J:278129
	neurodegeneration	J:278129
	Purkinje cell degeneration	J:278129
	thin cerebellar molecular layer	J:278129
Cacna1g^tm1.1Stl/Cacna1g^tm1.1Stl involves: C57BL/6	abnormal action potential	J:96099
	abnormal sleep duration	J:96099
	abnormal sleep pattern	J:96099
	decreased locomotor activity	J:96099
	fragmentation of sleep/wake states	J:96099
	impaired ability to fire action potentials	J:96099
Cacna1g^tm1.3Ksak/Cacna1g^tm1.3Ksak involves: C57BL/6	abnormal single cell response	J:151465
Cacna1g^tm1.3Ksak/Cacna1g^tm1.3Ksak involves: C57BL/6 * CBA	impaired behavioral response to xenobiotic	J:151612
Cacna1g^tm1Dgen/Cacna1g^tm1Dgen involves: 129/Sv * C57BL/6	decreased susceptibility to diet-induced obesity	J:150571
Cacna1g^tm1Dgen/Cacna1g^tm1Dgen involves: 129/Sv * C57BL/6	hyperactivity	J:150571
Cacna1g^tm1Hssh/Cacna1g^tm1Hssh involves: 129S1/Sv * 129S4/SvJae * 129X1/SvJ * C57BL/6J	impaired coordination	J:174980
	tremors	J:174980
Cacna1g^tm1Hssh/Cacna1g^tm1Hssh involves: 129S4/SvJae	abnormal atrioventricular node conduction	J:122634
	abnormal cardiovascular system physiology	J:122634
	abnormal sinoatrial node conduction	J:122634
	decreased heart rate	J:122634
	prolonged PQ interval	J:122634
Cacna1g^tm1Hssh/Cacna1g^tm1Hssh involves: 129S4/SvJae * C57BL/6J	abnormal action potential	J:70557
	abnormal nervous system physiology	J:70557
	abnormal spike wave discharge	J:70557
	decreased susceptibility to pharmacologically induced seizures	J:70557
Cacna1g^tm1Stl/Cacna1g^tm1Stl Tg(Camk2a-cre)CW2Stl/0 involves: C57BL/6	normal behavior/neurological phenotype	J:96099
Cacna1g^tm1Stl/Cacna1g^tm1Stl Tg(Kcnc2-cre)K128Stl/0 involves: C57BL/6	abnormal sleep pattern	J:96099
	fragmentation of sleep/wake states	J:96099

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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