Tapbp Phenotype Annotations

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Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Tapbp
TAP binding protein
MGI:1201689

10 phenotypes from 2 alleles in 3 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Tapbp^tm1Gjh/Tapbp^tm1Gjh involves: 129S2/SvPas	abnormal antigen presentation via MHC class I	J:64349
	abnormal dendritic cell antigen presentation	J:64349
	abnormal NK cell physiology	J:64349
	decreased cytotoxic T cell cytolysis	J:64349
	decreased level of surface class I molecules	J:64349
	decreased T cell number	J:64349
Tapbp^tm1Luc/Tapbp^tm1Luc involves: 129S6/SvEvTac	abnormal antigen presentation via MHC class I	J:64177
	abnormal cytotoxic T cell physiology	J:64177
	decreased CD8-positive, alpha-beta T cell number	J:64177
	decreased level of surface class I molecules	J:64177
	defective assembly of class I molecules	J:64177
Tapbp^tm1Luc/Tapbp^tm1Luc involves: 129S6/SvEvTac * C57BL/6	abnormal lymphocyte physiology	J:122479

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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