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Mammalian Phenotype Ontology Annotations
Query Results - Summary
Symbol
Name
ID 		Atp6v0d1
ATPase, H+ transporting, lysosomal V0 subunit D1
MGI:1201778
39 phenotypes from 2 alleles in 2 genetic backgrounds
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Allelic Composition
Genetic Background		 Annotated Term Reference
Atp6v0d1em1Nju/Atp6v0d1em1Nju
Tg(Adipoq-cre)1Evdr/0
involves: FVB/NJ 		abnormal cardiovascular system physiology J:346448
abnormal heart echocardiography feature J:346448
abnormal heart morphology J:346448
cardiac fibrosis J:346448
cardiac hypertrophy J:346448
decreased brown adipose tissue amount J:346448
decreased cardiac muscle contractility J:346448
decreased circulating adiponectin level J:346448
decreased circulating leptin level J:346448
decreased circulating triglyceride level J:346448
decreased epididymal fat pad weight J:346448
decreased inguinal fat pad weight J:346448
decreased retroperitoneal fat pad weight J:346448
decreased total body fat amount J:346448
enlarged heart J:346448
normal growth/size/body region phenotype J:346448
hepatic steatosis J:346448
improved glucose tolerance J:346448
increased circulating aspartate transaminase level J:346448
increased circulating cholesterol level J:346448
increased circulating free fatty acids level J:346448
increased fibroblast proliferation J:346448
increased liver cholesterol level J:346448
increased liver free fatty acids level J:346448
increased liver triglyceride level J:346448
increased liver weight J:346448
increased myocardial fiber size J:346448
insulin resistance J:346448
lipodystrophy J:346448
Atp6v0d1tm1b(EUCOMM)Hmgu/Atp6v0d1+
C57BL/6N-Atp6v0d1tm1b(EUCOMM)Hmgu/Tcp 		abnormal kidney morphology J:211773
abnormal seminal vesicle morphology J:211773
decreased lymphocyte cell number J:211773
decreased mean corpuscular hemoglobin concentration J:211773
increased neutrophil cell number J:211773
increased startle reflex J:211773
short tibia J:211773
Atp6v0d1tm1b(EUCOMM)Hmgu/Atp6v0d1tm1b(EUCOMM)Hmgu
C57BL/6N-Atp6v0d1tm1b(EUCOMM)Hmgu/Tcp 		embryonic lethality prior to organogenesis J:211773
embryonic lethality prior to tooth bud stage J:211773
preweaning lethality, complete penetrance J:211773
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
10/09/2024
MGI 6.24 		The Jackson Laboratory