Mmp8 Phenotype Annotations

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Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Mmp8
matrix metallopeptidase 8
MGI:1202395

9 phenotypes from 2 alleles in 4 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Mmp8^{tm1.1(KOMP)Vlcg}/Mmp8^{tm1.1(KOMP)Vlcg} C57BL/6N-Mmp8^{tm1.1(KOMP)Vlcg}/J	decreased circulating free fatty acids level	J:211773
	increased heart weight	J:211773
Mmp8^tm1Otin/Mmp8^tm1Otin involves: 129X1/SvJ	normal immune system phenotype	J:148442
Mmp8^tm1Otin/Mmp8^tm1Otin involves: 129X1/SvJ * C57BL/6	normal immune system phenotype	J:113463
Mmp8^tm1Otin/Mmp8^tm1Otin involves: 129X1/SvJ * C57BL/6J	abnormal inflammatory response	J:86393
	chronic inflammation	J:86393
	increased fibrosarcoma incidence	J:86393
	increased papilloma incidence	J:86393
	increased susceptibility to bacterial infection	J:97118
	increased tumor incidence	J:86393

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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