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Mammalian Phenotype Ontology Annotations
Query Results - Summary
Symbol
Name
ID 		Tert
telomerase reverse transcriptase
MGI:1202709
25 phenotypes from 8 alleles in 9 genetic backgrounds
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Allelic Composition
Genetic Background		 Annotated Term Reference
Terttm1.1Phan/Terttm1.1Phan
Tg(Col1a2-cre/ERT,-ALPP)7Cpd/0
involves: C57BL/6 * DBA/2 		decreased lung fibroblast proliferation J:239734
increased apoptosis J:239734
pulmonary fibrosis J:239734
Terttm1Fish/Terttm1Fish
involves: 129S7/SvEvBrd * C57BL/6 		no abnormal phenotype detected J:59858
Terttm1Leah/Tert+
involves: 129P2/OlaHsd * C57BL/6J 		abnormal telomere length J:90866
aneuploidy J:90866
Terttm1Leah/Terttm1Leah
involves: 129P2/OlaHsd * C57BL/6J 		abnormal telomere length J:90866
aneuploidy J:90866
chromosomal instability J:90866
Terttm1Rdp/Terttm1Rdp
B6.Cg-Terttm1Rdp 		abnormal chromosome morphology J:108914
decreased incidence of tumors by chemical induction J:108914
decreased litter size J:108914
decreased liver tumor incidence J:108914
decreased telomere length J:108914
increased apoptosis J:108914
reduced fertility J:108914
testicular atrophy J:108914
Terttm1Sear/Terttm1Sear
involves: 129S4/SvJae * C57BL/6 		abnormal telomere length J:127153
increased apoptosis J:127153
Terttm1Sear/Terttm1Sear
Not Specified 		decreased rib number J:150343
lumbar vertebral transformation J:150343
thoracic vertebral transformation J:150343
Terttm1Yjc/Tert+
involves: C57BL/6 * SPRET/Ei 		normal cellular phenotype J:92243
Terttm1Yjc/Terttm1Yjc
involves: 129/Sv * C57BL/6 * SJL * SPRET/Ei 		abnormal telomere length J:92243
Terttm1Yjc/Terttm1Yjc
involves: C57BL/6 * SPRET/Ei 		abnormal telomere length J:92243
Terttm3Rdp/Terttm3Rdp
involves: C57BL/6 		decreased body weight J:186105
decreased cell proliferation J:186105
decreased testis weight J:186105
increased apoptosis J:186105
increased small intestinal crypt cell apoptosis J:186105
testicular atrophy J:186105
Tg(KRT5-Tert)8043Blas/0
involves: C57BL/6 * DBA/2 		normal cellular phenotype J:69757
enhanced wound healing J:69757, J:96945
increased incidence of tumors by chemical induction J:69757, J:96945
skin hyperplasia J:69757, J:96945
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
11/12/2024
MGI 6.24 		The Jackson Laboratory