Tcf21 Phenotype Annotations - Multigenic Genotypes

Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Tcf21
transcription factor 21
MGI:1202715

24 phenotypes from multigenic genotypes

Allelic Composition Genetic Background	Annotated Term	Reference
Ctnnb1^tm1Mmt/Ctnnb1^tm1Mmt Tcf21^tm1(cre)Seq/Tcf21⁺ involves: 129S1/Sv * 129X1/SvJ	abnormal kidney development	J:189643
	hydroureter	J:189643
	kidney cyst	J:189643
	neonatal lethality	J:189643
	renal hypoplasia	J:189643
	ureter hypoplasia	J:189643
Ctnnb1^tm2Kem/Ctnnb1^tm2Kem Tcf21^tm1(cre)Seq/Tcf21⁺ involves: 129S1/Sv * 129X1/SvJ	abnormal kidney development	J:189643
	fused kidneys	J:189643
	increased tumor incidence	J:189643
	prenatal lethality	J:189643
	renal hypoplasia	J:189643
Msc^tm1Eno/Msc⁺ Tcf21^tm2Eno/Tcf21^tm2Eno involves: 129 * Black Swiss	normal muscle phenotype	J:111337
Msc^tm1Eno/Msc^tm1Eno Tcf21^tm2Eno/Tcf21⁺ involves: 129 * Black Swiss	no abnormal phenotype detected	J:111337
Msc^tm1Eno/Msc^tm1Eno Tcf21^tm2Eno/Tcf21^tm2Eno involves: 129 * Black Swiss	abnormal masticatory muscle morphology	J:111337
	abnormal myogenesis	J:111337
	abnormal palatal shelf elevation	J:111337
	abnormal pterygoid muscle morphology	J:111337
	absent masseter muscle	J:111337
	absent pterygoid muscle	J:111337
	absent temporalis muscle	J:111337
	cleft secondary palate	J:111337
	diaphragmatic hernia	J:111337
	neonatal lethality, complete penetrance	J:111337
Ptch1^tm1Bjw/Ptch1^tm1Bjw Tcf21^tm1(cre)Seq/Tcf21⁺ involves: 129S1/Sv * 129T2/SvEms * 129X1/SvJ	abnormal kidney collecting duct morphology	J:189643
	abnormal kidney morphology	J:189643
	abnormal kidney pelvis morphology	J:189643
	increased tumor incidence	J:189643
	kidney cyst	J:189643
	prenatal lethality	J:189643

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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