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Mammalian Phenotype Ontology Annotations
Query Results - Summary
Symbol
Name
ID 		Gtf2i
general transcription factor II I
MGI:1202722
34 phenotypes from 7 alleles in 5 genetic backgrounds
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Allelic Composition
Genetic Background		 Annotated Term Reference
Gtf2iGt(RRI105)Byg/Gtf2iGt(RRI105)Byg
involves: 129P2/OlaHsd * C57BL/6 		embryonic lethality, complete penetrance J:143508
Gtf2iGt(XC455)Byg/Gtf2iGt(XC455)Byg
involves: 129P2/OlaHsd * C57BL/6 		embryonic lethality, complete penetrance J:143508
Gtf2iGt(XE029)Byg/Gtf2i+
involves: 129P2/OlaHsd * C57BL/6 		abnormal craniofacial morphology J:143508
decreased body size J:143508
exencephaly J:143508
narrow head J:143508
Gtf2iGt(XE029)Byg/Gtf2iGt(XE029)Byg
involves: 129P2/OlaHsd * C57BL/6 		abnormal brain development J:143508
decreased embryo size J:143508
dilated allantois J:143508
distended pericardium J:143508
embryonic growth retardation J:143508
embryonic lethality, complete penetrance J:143508
exencephaly J:143508
failure of chorioallantoic fusion J:143508
failure of heart looping J:143508
internal hemorrhage J:143508
midline facial cleft J:143508
pharyngeal arch hypoplasia J:143508
Gtf2iGt(YTA365)Byg/Gtf2iGt(YTA365)Byg
involves: 129P2/OlaHsd * CD-1 		embryonic lethality, complete penetrance J:196809
Gtf2itm1.1Bdash/Gtf2itm1.1Bdash
involves: 129S4/SvJaeSor * 129S6/SvEvTac * C57BL/6J 		no abnormal phenotype detected J:236328
Gtf2itm1.2Bdash/Gtf2itm1.2Bdash
involves: 129S1/Sv * 129S4/SvJaeSor * 129S6/SvEvTac * C57BL/6J 		embryonic lethality during organogenesis, complete penetrance J:236328
Gtf2itm1Vcam/Gtf2i+
involves: 129S1/Sv * 129X1/SvJ * CD-1 		abnormal behavior J:204278
normal behavior/neurological phenotype J:204278
decreased exploration in new environment J:204278
decreased vertical activity J:204278
increased anxiety-related response J:204278
Gtf2itm1Vcam/Gtf2itm1Vcam
involves: 129S1/Sv * 129X1/SvJ * CD-1 		abnormal craniofacial morphology J:204278
abnormal embryo development J:204278
absent embryonic epiblast J:204278
normal behavior/neurological phenotype J:204278
broad nasal bridge J:204278
decreased embryonic epiblast cell proliferation J:204278
embryonic lethality, incomplete penetrance J:204278
normal nervous system phenotype J:204278
prenatal lethality, incomplete penetrance J:204278
reduced female fertility J:204278
reduced male fertility J:204278
short snout J:204278
small testis J:204278
testicular atrophy J:204278
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
11/19/2024
MGI 6.24 		The Jackson Laboratory