Myoc Phenotype Annotations

About Help FAQ

Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Myoc
myocilin
MGI:1202864

12 phenotypes from 4 alleles in 6 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Myoc^tm1.1Rjo/Myoc^tm1.1Rjo involves: 129S7/SvEvBrd * C57BL/6	no abnormal phenotype detected	J:72628
Myoc^tm1Rjo/Myoc^tm1Rjo either: 129S7/SvEvBrd or (involves: 129S7/SvEvBrd * C57BL/6)	no abnormal phenotype detected	J:72628
Myoc^tm2.1Rjo/Myoc^tm2.1Rjo either: (involves: 129S7/SvEvBrd * AKR/J * C57BL/6J) or (involves: 129S7/SvEvBrd * BALB/c * C57BL/6J)	normal vision/eye phenotype	J:115971
Myoc^tm2.1Rjo/Myoc^tm2.1Rjo involves: 129S7/SvEvBrd * C57BL/6J	abnormal intraocular pressure	J:115971
	normal vision/eye phenotype	J:115971
Myoc^tm2.1Rjo/Myoc^tm2.1Rjo involves: 129S7/SvEvBrd * C57BL/6J * CBA/CaJ	normal vision/eye phenotype	J:115971
Tg(MyocY423H)#Sit/0 B6.FVB-Tg(MyocY423H)#Sit	abnormal canal of Schlemm morphology	J:116124
	abnormal retina inner plexiform layer morphology	J:116124
	abnormal retina neuronal layer morphology	J:116124
	abnormal trabecular meshwork morphology	J:116124
	astrocytosis	J:116124
	axon degeneration	J:116124
	ocular hypertension	J:116124
	optic nerve degeneration	J:116124
	retina ganglion cell degeneration	J:116124

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources Funding Information Warranty Disclaimer, Privacy Notice, Licensing, & Copyright Send questions and comments to User Support.	last database update 12/10/2024 MGI 6.24