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Mammalian Phenotype Ontology Annotations
Query Results - Summary
Symbol
Name
ID 		Tcf7l2
transcription factor 7 like 2, T cell specific, HMG box
MGI:1202879
15 phenotypes from multigenic genotypes
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Allelic Composition
Genetic Background		 Annotated Term Reference
ApcMin/Apc+
Tcf7l2tm1.1(EGFP/cre)Mrc/Tcf7l2+
involves: 129S1/Sv * 129X1/SvJ * C57BL/6J 		increased intestinal adenoma incidence J:170088
ApcMin/Apc+
Tcf7l2tm2.2Mrc/Tcf7l2+
involves: C57BL/6J 		increased intestinal adenoma incidence J:170088
ApcMin/Apc+
Tcf7l2tm1(EGFP/cre)Mrc/Tcf7l2tm2.1Mrc
involves: 129S1/Sv * 129S6/SvEvTac * 129X1/SvJ * C57BL/6J * C57BL/6NCrl 		normal neoplasm J:170088
Tcf7tm1Cle/Tcf7tm1Cle
Tcf7l1tm1Efu/Tcf7l1tm1Efu
Tcf7l2tm2.1Cle/Tcf7l2tm2.1Cle
Tg(Vil1-cre/ERT2)23Syr/0
involves: 129P2/OlaHsd * C57BL/6 * DBA/2 		abnormal digestive system morphology J:185753
abnormal digestive system physiology J:185753
Tcf7l1tm1.1Efu/Tcf7l1tm1.1Efu
Tcf7l2tm1Cle/Tcf7l2tm1Cle
Tg(KRT14-cre)1Efu/0
involves: 129/Sv * 129P2/OlaHsd 		abnormal epidermis stratum basale morphology J:155012
abnormal hair follicle morphology J:155012
abnormal skin physiology J:155012
absent hair follicles J:155012
absent vibrissae J:155012
decreased keratinocyte proliferation J:155012
thin epidermis J:155012
thin skin J:155012
Tcf7l2tm3.1(cre/ERT2)Mrc/Tcf7l2+
Gt(ROSA)26Sortm1(DTA)Mrc/Gt(ROSA)26Sor+
involves: 129S1/Sv * 129X1/SvJ * C57BL/6 		abnormal muscle morphology J:174914
abnormal muscle regeneration J:174914
decreased satellite cell number J:174914
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
11/12/2024
MGI 6.24 		The Jackson Laboratory