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Mammalian Phenotype Ontology Annotations
Query Results - Summary
Symbol
Name
ID 		Cd46
CD46 antigen, complement regulatory protein
MGI:1203290
14 phenotypes from 3 alleles in 3 genetic backgrounds
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Allelic Composition
Genetic Background		 Annotated Term Reference
Cd46em1(IMPC)H/Cd46em1(IMPC)H
C57BL/6NTac-Cd46em1(IMPC)H/H 		prolonged RR interval J:211773
Cd46tm1Atk/Cd46tm1Atk
B6.129-Cd46tm1Atk 		abnormal Bruch membrane morphology J:234294
abnormal choriocapillaris morphology J:234294
abnormal optic choroid morphology J:234294
abnormal retina morphology J:213630, J:234294
abnormal retina outer nuclear layer morphology J:234294
abnormal retina photoreceptor morphology J:234294
abnormal retina pigment epithelium morphology J:234294
increased susceptibility to age-related retinal degeneration J:234294
increased susceptibility to induced choroid neovascularization J:213630
normal reproductive system phenotype J:213630
retina photoreceptor degeneration J:234294
Cd46tm1Osb/Cd46tm1Osb
involves: 129S2/SvPas * C57BL/6 		abnormal fertilization J:82516
increased litter size J:82516
normal reproductive system phenotype J:82516
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
11/12/2024
MGI 6.24 		The Jackson Laboratory