About   Help   FAQ
Mammalian Phenotype Ontology Annotations
Query Results - Summary
Symbol
Name
ID 		Bap1
Brca1 associated protein 1
MGI:1206586
49 phenotypes from 6 alleles in 4 genetic backgrounds
Export: Excel File
Allelic Composition
Genetic Background		 Annotated Term Reference
Bap1em1Test/Bap1+
involves: FVB 		abnormal DNA methylation J:213725
abnormal epigenetic regulation of gene expression J:213725
normal hematopoietic system phenotype J:213725
increased colon tumor incidence J:231692
increased granulosa cell tumor incidence J:231692
increased incidence of tumors by chemical induction J:213725
increased lung carcinoma incidence J:231692
increased mammary adenocarcinoma incidence J:231692
increased mesothelioma incidence J:231692
increased ovary tumor incidence J:231692
increased skin tumor incidence J:231692
increased squamous cell carcinoma incidence J:213725
Bap1em1Test/Bap1em1Test
involves: FVB 		embryonic lethality between implantation and placentation, complete penetrance J:213725
Bap1em2Test/Bap1+
involves: FVB 		increased granulosa cell tumor incidence J:231692
increased incidence of tumors by chemical induction J:231692
increased lung carcinoma incidence J:231692
increased mammary adenocarcinoma incidence J:231692
increased mesothelioma incidence J:231692
increased ovary tumor incidence J:231692
increased pancreatic islet cell carcinoma incidence J:231692
increased skin tumor incidence J:231692
Bap1em3Test/Bap1+
involves: FVB 		increased granulosa cell tumor incidence J:231692
increased incidence of tumors by chemical induction J:231692
increased lung carcinoma incidence J:231692
increased lymphoma incidence J:231692
increased mammary adenocarcinoma incidence J:231692
increased ovary tumor incidence J:231692
increased skin tumor incidence J:231692
Bap1tm1.1Geno/Bap1+
Gt(ROSA)26Sortm9(cre/ESR1)Arte/Gt(ROSA)26Sor+
involves: C57BL/6 * C57BL/6NTac 		abnormal hematopoietic system morphology/development J:187380
Bap1tm1.1Geno/Bap1tm1.1Geno
Gt(ROSA)26Sortm9(cre/ESR1)Arte/Gt(ROSA)26Sor+
involves: C57BL/6 * C57BL/6NTac 		abnormal bone marrow cell physiology J:187380
abnormal cardiac thrombosis J:187380
abnormal erythrocyte morphology J:187380
abnormal erythropoiesis J:187380
abnormal granulocyte morphology J:187380
abnormal hematopoietic stem cell physiology J:187380
abnormal myelopoiesis J:187380
abnormal neutrophil morphology J:187380
anemia J:187380
anisopoikilocytosis J:187380
cardiac muscle necrosis J:187380
enlarged spleen J:187380
extramedullary hematopoiesis J:187380
giant platelets J:187380
heart inflammation J:187380
increased hematopoietic stem cell number J:187380
increased leukemia incidence J:187380
increased leukocyte cell number J:187380
increased monocyte cell number J:187380
increased neutrophil cell number J:187380
increased nucleated erythrocyte cell number J:187380
myeloid hyperplasia J:187380
thrombocytopenia J:187380
Bap1tm1.2Geno/Bap1tm1.2Geno
involves: C57BL/6 		embryonic growth retardation J:187380
embryonic lethality during organogenesis, complete penetrance J:187380
Bap1tm1a(EUCOMM)Hmgu/Bap1+
C57BL/6N-Bap1tm1a(EUCOMM)Hmgu/Wtsi 		abnormal vibrissa morphology J:211773
Bap1tm1a(EUCOMM)Hmgu/Bap1tm1a(EUCOMM)Hmgu
C57BL/6N-Bap1tm1a(EUCOMM)Hmgu/Wtsi 		abnormal chorion morphology J:261316
abnormal placenta morphology J:261316
abnormal trophoblast layer morphology J:261316
abnormal visceral yolk sac morphology J:261316
embryonic lethality during organogenesis, incomplete penetrance J:261316
lethality throughout fetal growth and development, complete penetrance J:261316
preweaning lethality, complete penetrance J:211773
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
Send questions and comments to User Support. 		last database update
11/12/2024
MGI 6.24 		The Jackson Laboratory