About   Help   FAQ
Mammalian Phenotype Ontology Annotations
Query Results - Summary
Symbol
Name
ID 		Suz12
SUZ12 polycomb repressive complex 2 subunit
MGI:1261758
38 phenotypes from 4 alleles in 5 genetic backgrounds
Export: Excel File
Allelic Composition
Genetic Background		 Annotated Term Reference
Suz12Gt(Betageo)1Khe/Suz12+
involves: 129P2/OlaHsd 		increased histiocytic sarcoma incidence J:217077
Suz12Gt(Betageo)1Khe/Suz12Gt(Betageo)1Khe
involves: 129P2/OlaHsd * C57BL/6 		abnormal amnion morphology J:93307
abnormal amniotic cavity morphology J:93307
abnormal chorion morphology J:93307
abnormal developmental patterning J:93307
abnormal ectoplacental cavity morphology J:93307
abnormal embryonic neuroepithelium morphology J:93307
abnormal extraembryonic coelom morphology J:93307
abnormal extraembryonic tissue morphology J:93307
decreased cell proliferation J:93307
decreased embryo size J:93307
embryonic growth arrest J:93307
embryonic lethality, complete penetrance J:93307
increased embryonic tissue cell apoptosis J:93307
Suz12Gt(Betageo)1Khe/Suz12Plt8
involves: 129P2/OlaHsd * 129S1/Sv * C57BL/6 		preweaning lethality, complete penetrance J:136262
Suz12Plt8/Suz12+
involves: 129 * C57BL/6 		increased leukocyte cell number J:136262
increased lymphocyte cell number J:136262
thrombocytosis J:136262
Suz12tm1Hko/Suz12+
Not Specified 		cervical vertebral transformation J:170279
lumbar vertebral transformation J:170279
thoracic vertebral transformation J:170279
vertebral transformation J:170279
Suz12tm1Hko/Suz12tm1Hko
Not Specified 		abnormal extraembryonic tissue morphology J:109525
decreased embryo size J:109525
embryonic lethality between somite formation and embryo turning, complete penetrance J:170279
embryonic lethality, complete penetrance J:109525
Suz12tm1Xmir/Suz12+
Not Specified 		abnormal brain morphology J:150128
abnormal cerebellum morphology J:150128
abnormal cerebral cortex morphology J:150128
abnormal hippocampus morphology J:150128
abnormal posture J:150128
abnormal stratification in cerebral cortex J:150128
decreased corpus callosum size J:150128
diastematomyelia J:150128
enlarged tectum J:150128
hindlimb paralysis J:150128
hydrocephaly J:150128
increased inferior colliculus size J:150128
increased superior colliculus size J:150128
spina bifida J:150128
Suz12tm1Xmir/Suz12tm1Xmir
Not Specified 		embryonic lethality during organogenesis, complete penetrance J:150128
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
Send questions and comments to User Support. 		last database update
09/24/2024
MGI 6.24 		The Jackson Laboratory