Myo15a Phenotype Annotations

Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Myo15a
myosin XVA
MGI:1261811

36 phenotypes from 9 alleles in 11 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Myo15a^m1Btlr/Myo15a^m1Btlr C57BL/6J-Myo15a^m1Btlr	circling	J:203906
	head bobbing	J:203906
	head tilt	J:203906
	impaired coordination	J:203906
Myo15a^m2Btlr/Myo15a^m2Btlr C57BL/6J-Myo15a^m2Btlr	ataxia	J:255209
	circling	J:255209
	head tilt	J:255209
Myo15a^mpc190H/Myo15a^mpc190H involves: BALB/c * C3H/HeH * C57BL/6J	deafness	J:234901
Myo15a^sh2-2J/Myo15a^sh2-2J involves: STOCK Rb(16.17)7Bnr	circling	J:69998
Myo15a^sh2-2J/Myo15a^sh2-2J involves: STOCK Rb(16.17)7Bnr	deafness	J:69998
Myo15a^sh2-3J/Myo15a^sh2-3J C57BL/6J-Myo15a^sh2-3J/J	abnormal motor capabilities/coordination/movement	J:96071
	absent cochlear hair cells	J:96071
	circling	J:96071
	cochlear ganglion hypoplasia	J:96071
	deafness	J:96071
	head bobbing	J:96071
	normal hearing/vestibular/ear phenotype	J:96071
	impaired swimming	J:96071
Myo15a^sh2-J/Myo15a^tm1.1Jebd involves: C57BL/6 * C57BLKS * FVB/N	cochlear hair cell degeneration	J:226820
	deafness	J:226820
	increased or absent threshold for auditory brainstem response	J:226820
Myo15a^sh2/Myo15a^sh2 Mixed stock	abnormal cochlear outer hair cell morphology	J:158897
Myo15a^sh2/Myo15a^sh2 Mixed stock	short outer hair cell stereocilia	J:132633, J:158897
Myo15a^sh2/Myo15a^sh2 Not Specified	abnormal cochlear ganglion morphology	J:13046
	abnormal cochlear hair cell morphology	J:6873, J:13046
	abnormal organ of Corti morphology	J:13046
	abnormal stria vascularis morphology	J:13046
	abnormal tectorial membrane morphology	J:13046
	abnormal utricular macula morphology	J:13046
	circling	J:13046
	cochlear ganglion degeneration	J:13046
	deafness	J:13046
	head shaking	J:13046
	organ of Corti degeneration	J:13046
Myo15a^sh2/Myo15a^sh2 STOCK Myo15a^sh2/J	abnormal cochlear hair cell inter-stereocilial links morphology	J:226820
	abnormal inner hair cell stereociliary bundle morphology	J:226820
	short inner hair cell stereocilia	J:226820
Myo15a^tm1.1Jebd/Myo15a^tm1.1Jebd involves: C57BL/6 * FVB/N	abnormal cochlear hair cell morphology	J:226820
	abnormal cochlear inner hair cell physiology	J:226820
	absent distortion product otoacoustic emissions	J:226820
	cochlear hair cell degeneration	J:226820
	deafness	J:226820
	increased or absent threshold for auditory brainstem response	J:226820
	short cochlear hair cell stereocilia	J:226820
	thin cochlear hair cell stereocilia	J:226820
Myo15a^{tm1a(EUCOMM)Wtsi}/Myo15a^{tm1a(EUCOMM)Wtsi} C57BL/6N-Myo15a^{tm1a(EUCOMM)Wtsi}/Wtsi	abnormal lens morphology	J:211773
	absent pinna reflex	J:211773
	cataract	J:211773
	increased grip strength	J:211773
	increased total body fat amount	J:211773

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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