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Mammalian Phenotype Ontology Annotations
Query Results - Summary
Symbol
Name
ID 		Zfp106
zinc finger protein 106
MGI:1270153
57 phenotypes from 5 alleles in 4 genetic backgrounds
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Allelic Composition
Genetic Background		 Annotated Term Reference
Tg(Mnx1-Zfp106,-EGFP)1Blk/0
Zfp106tm1b(KOMP)Wtsi/Zfp106tm1b(KOMP)Wtsi
involves: C57BL/6N 		abnormal body weight J:241305
abnormal motor capabilities/coordination/movement J:241305
abnormal motor neuron morphology J:241305
abnormal muscle fiber morphology J:241305
Tg(Mnx1-Zfp106,-EGFP)2Blk/0
Zfp106tm1b(KOMP)Wtsi/Zfp106tm1b(KOMP)Wtsi
involves: C57BL/6N 		abnormal body weight J:241305
abnormal motor capabilities/coordination/movement J:241305
abnormal motor neuron morphology J:241305
abnormal muscle fiber morphology J:241305
Zfp106em1Blk/Zfp106em1Blk
Not Specified 		abnormal physical strength J:241305
abnormal skeletal muscle morphology J:241305
cachexia J:241305
decreased grip strength J:241305
decreased motor neuron number J:241305
skeletal muscle fiber atrophy J:241305
skeletal muscle fiber degeneration J:241305
Zfp106tm1a(KOMP)Wtsi/Zfp106+
B6JTyr;B6N-Zfp106tm1a(KOMP)Wtsi/Wtsi 		decreased mean corpuscular hemoglobin J:165965
increased circulating calcium level J:175295
Zfp106tm1a(KOMP)Wtsi/Zfp106tm1a(KOMP)Wtsi
B6JTyr;B6N-Zfp106tm1a(KOMP)Wtsi/Wtsi 		abnormal external male genitalia morphology J:175295
abnormal gait J:165965
decreased body weight J:165965
increased thermal nociceptive threshold J:165965
Zfp106tm1a(KOMP)Wtsi/Zfp106tm1a(KOMP)Wtsi
involves: C57BL/6Brd * C57BL/6Dnk * C57BL/6N 		abnormal axon morphology J:229162
abnormal gait J:229162
abnormal gastrocnemius morphology J:229162
abnormal lumbar dorsal root ganglion morphology J:229162
abnormal mitochondrial ATP synthesis coupled electron transport J:229162
abnormal mitochondrial physiology J:229162
abnormal muscle electrophysiology J:229162
abnormal muscle physiology J:229162
abnormal redox activity J:229162
abnormal skeletal muscle fiber type ratio J:229162
abnormal soleus morphology J:229162
abnormal spinal cord morphology J:229162
astrocytosis J:229162
axon degeneration J:229162
centrally nucleated skeletal muscle fibers J:229162
chromatolysis J:229162
decreased gastrocnemius weight J:229162
decreased grip strength J:229162
decreased locomotor activity J:229162
decreased skeletal muscle fiber number J:229162
decreased soleus weight J:229162
decreased tibialis anterior weight J:229162
gliosis J:229162
impaired coordination J:229162
impaired limb coordination J:229162
increased spinal cord apoptosis J:229162
increased variability of skeletal muscle fiber size J:229162
kyphosis J:229162
limb grasping J:229162
microgliosis J:229162
motor neuron degeneration J:229162
normal nervous system phenotype J:229162
neurodegeneration J:229162
positive geotaxis J:229162
premature death J:229162
skeletal muscle atrophy J:229162
skeletal muscle fiber atrophy J:229162
skeletal muscle fibrosis J:229162
small dorsal root ganglion J:229162
small L4 dorsal root ganglion J:229162
small L5 dorsal root ganglion J:229162
tremors J:229162
weight loss J:229162
Zfp106tm1b(KOMP)Wtsi/Zfp106tm1b(KOMP)Wtsi
involves: C57BL/6N 		abnormal physical strength J:241305
abnormal skeletal muscle morphology J:241305
cachexia J:241305
decreased grip strength J:241305
decreased motor neuron number J:241305
skeletal muscle fiber atrophy J:241305
skeletal muscle fiber degeneration J:241305
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
11/19/2024
MGI 6.24 		The Jackson Laboratory