Il12rb2 Phenotype Annotations - Multigenic Genotypes

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Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Il12rb2
interleukin 12 receptor, beta 2
MGI:1270861

8 phenotypes from multigenic genotypes

Allelic Composition Genetic Background	Annotated Term	Reference
Il12rb2^Ifnm-d/Il12rb2^Ifnm-d Tlr4^lps-del/Tlr4^lps-del C57BL/10ScCr	abnormal dendritic cell physiology	J:91014
	abnormal granulocyte physiology	J:91014
	abnormal immune cell physiology	J:91014
	abnormal macrophage physiology	J:91014
	abnormal NK cell physiology	J:91014
	decreased interferon-gamma secretion	J:70821, J:91014
	increased interleukin-4 secretion	J:91014
	increased susceptibility to bacterial infection	J:70821, J:91014

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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