Cldn2 Phenotype Annotations

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Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Cldn2
claudin 2
MGI:1276110

15 phenotypes from 2 alleles in 2 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Cldn2^tm1Lex/Y B6J.129S5-Cldn2^tm1Lex	abnormal enzyme/coenzyme level	J:237065
	abnormal renal sodium ion transport	J:237065
	abnormal renal sodium reabsorption	J:237065
	hypoxia	J:237065
	increased blood urea nitrogen level	J:237065
	increased circulating creatinine level	J:237065
	increased oxygen consumption	J:237065
	increased susceptibility to kidney reperfusion injury	J:237065
	increased urine sodium level	J:237065
Cldn2^tm1Muto/Cldn2^tm1Muto involves: 129S4/SvJae * C57BL/6	abnormal renal reabsorption	J:159379
	abnormal renal sodium reabsorption	J:159379
	abnormal renal water reabsorption	J:159379
	decreased urine osmolality	J:159379
	increased urine calcium level	J:159379
	increased urine sodium level	J:159379
	polyuria	J:159379
	normal renal/urinary system phenotype	J:159379

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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