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Mammalian Phenotype Ontology Annotations
Query Results - Summary
Symbol
Name
ID 		Cldn2
claudin 2
MGI:1276110
15 phenotypes from 2 alleles in 2 genetic backgrounds
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Allelic Composition
Genetic Background		 Annotated Term Reference
Cldn2tm1Lex/Y
B6J.129S5-Cldn2tm1Lex 		abnormal enzyme/coenzyme level J:237065
abnormal renal sodium ion transport J:237065
abnormal renal sodium reabsorption J:237065
hypoxia J:237065
increased blood urea nitrogen level J:237065
increased circulating creatinine level J:237065
increased oxygen consumption J:237065
increased susceptibility to kidney reperfusion injury J:237065
increased urine sodium level J:237065
Cldn2tm1Muto/Cldn2tm1Muto
involves: 129S4/SvJae * C57BL/6 		abnormal renal reabsorption J:159379
abnormal renal sodium reabsorption J:159379
abnormal renal water reabsorption J:159379
decreased urine osmolality J:159379
increased urine calcium level J:159379
increased urine sodium level J:159379
polyuria J:159379
normal renal/urinary system phenotype J:159379
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
09/24/2024
MGI 6.24 		The Jackson Laboratory