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Mammalian Phenotype Ontology Annotations
Query Results - Summary
Symbol
Name
ID 		Ncoa2
nuclear receptor coactivator 2
MGI:1276533
43 phenotypes from 3 alleles in 4 genetic backgrounds
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Allelic Composition
Genetic Background		 Annotated Term Reference
Ncoa2em1(IMPC)Mbp/Ncoa2+
C57BL/6N-Ncoa2em1(IMPC)Mbp/MbpMmucd 		abnormal auditory brainstem response J:211773
abnormal behavior J:211773
abnormal kidney morphology J:211773
abnormal placenta morphology J:211773
abnormal placenta vasculature J:211773
abnormal skin morphology J:211773
abnormal spleen morphology J:211773
decreased anxiety-related response J:211773
decreased locomotor activity J:211773
decreased thigmotaxis J:211773
enlarged spleen J:211773
hyperactivity J:211773
increased circulating insulin level J:211773
increased neutrophil cell number J:211773
no spontaneous movement J:211773
small kidney J:211773
Ncoa2em1(IMPC)Mbp/Ncoa2em1(IMPC)Mbp
C57BL/6N-Ncoa2em1(IMPC)Mbp/MbpMmucd 		abnormal body wall morphology J:211773
abnormal placenta morphology J:211773
abnormal tail morphology J:211773
abnormal umbilical cord morphology J:211773
no spontaneous movement J:211773
preweaning lethality, incomplete penetrance J:211773
Ncoa2tm1.1Ipc/Ncoa2tm1.1Ipc
Pgrtm2(cre)Lyd/Pgr+
involves: 129S1/Sv * 129S2/SvPas * 129X1/SvJ 		abnormal branching of the mammary ductal tree J:117006
abnormal decidualization J:117006
failure of embryo implantation J:117006
female infertility J:117006
normal reproductive system phenotype J:117006
Ncoa2tm1.2Ipc/Ncoa2tm1.2Ipc
involves: 129S2/SvPas * C57BL/6 		abnormal epididymis morphology J:78075
abnormal reproductive system morphology J:78075
abnormal reproductive system physiology J:78075
abnormal rete testis morphology J:78075
abnormal seminiferous tubule morphology J:78075
abnormal Sertoli cell morphology J:78075, J:101966
abnormal spermatid morphology J:78075
abnormal testis morphology J:78075
normal behavior/neurological phenotype J:78075
decreased body size J:78075
decreased body weight J:78075
decreased litter size J:78075
decreased testis weight J:78075
detached acrosome J:78075
reduced female fertility J:78075
reduced male fertility J:78075
normal reproductive system phenotype J:78075
teratozoospermia J:78075
Ncoa2tm1.2Ipc/Ncoa2tm1.2Ipc
involves: 129S2/SvPas * C57BL/6J 		normal immune system phenotype J:109522
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
11/12/2024
MGI 6.24 		The Jackson Laboratory