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Mammalian Phenotype Ontology Annotations
Query Results - Summary
Symbol
Name
ID 		Ptp4a2
protein tyrosine phosphatase 4a2
MGI:1277117
48 phenotypes from 3 alleles in 3 genetic backgrounds
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Allelic Composition
Genetic Background		 Annotated Term Reference
Ptp4a2em1(IMPC)Tcp/Ptp4a2em1(IMPC)Tcp
C57BL/6N-Ptp4a2em1(IMPC)Tcp/Tcp 		abnormal bone structure J:211773
abnormal skin morphology J:211773
abnormal stomach morphology J:211773
decreased body length J:211773
decreased lean body mass J:211773
decreased mean corpuscular volume J:211773
decreased prepulse inhibition J:211773
enlarged lymph nodes J:211773
increased grip strength J:211773
increased mean platelet volume J:211773
increased total body fat amount J:211773
short tibia J:211773
shortened QRS complex duration J:211773
small testis J:211773
thick skin J:211773
Ptp4a2Gt(AQ0673)Wtsi/Ptp4a2Gt(AQ0673)Wtsi
involves: 129P2/OlaHsd * C57BL/6 		abnormal cauda epididymis morphology J:209512, J:250112
abnormal male germ cell physiology J:209512
abnormal maternal decidual layer morphology J:190411
abnormal seminiferous tubule epithelium morphology J:209512
abnormal seminiferous tubule morphology J:209512, J:250112
abnormal spermatogenesis J:209512
decreased birth body size J:190411
decreased birth weight J:190411
decreased body size J:209512
decreased body weight J:190411
decreased cell proliferation J:190411
decreased fetal weight J:190411
decreased litter size J:209512
decreased male germ cell number J:209512, J:250112
decreased placenta weight J:190411
decreased placental labyrinth size J:190411
decreased spleen weight J:190411
decreased spongiotrophoblast size J:190411
decreased testis weight J:190411, J:209512, J:250112
decreased trophoblast glycogen cell number J:190411
normal homeostasis/metabolism phenotype J:209512
increased male germ cell apoptosis J:209512, J:250112
male infertility J:209512
oligozoospermia J:209512, J:250112
postnatal growth retardation J:190411
preweaning lethality, incomplete penetrance J:250112
reduced male fertility J:209512
normal reproductive system phenotype J:209512, J:250112
slow postnatal weight gain J:250112
small seminiferous tubules J:209512, J:250112
small testis J:209512, J:250112
testicular atrophy J:209512
Ptp4a2Gt(AQ0673)Wtsi/Ptp4a2Gt(AQ0673)Wtsi
Tg(CAG-Ptp4a2,-EGFP)11Zyz/0
involves: 129P2/OlaHsd * C57BL/6 * FVB/N 		normal growth/size/body region phenotype J:250112
normal mortality/aging J:250112
normal reproductive system phenotype J:250112
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
11/12/2024
MGI 6.24 		The Jackson Laboratory