Vax1 Phenotype Annotations

Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Vax1
ventral anterior homeobox 1
MGI:1277163

55 phenotypes from 3 alleles in 5 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Vax1^{tm1b(KOMP)Mbp}/Vax1⁺ C57BL/6N-Vax1^{tm1b(KOMP)Mbp}/J	abnormal sinus arrhythmia	J:211773
	decreased circulating glucose level	J:211773
	increased circulating alkaline phosphatase level	J:211773
Vax1^{tm1b(KOMP)Mbp}/Vax1^{tm1b(KOMP)Mbp} C57BL/6N-Vax1^{tm1b(KOMP)Mbp}/J	preweaning lethality, incomplete penetrance	J:211773
Vax1^tm1Grl/Vax1^tm1Grl involves: 129S1/Sv	coloboma	J:98488
Vax1^tm1Grl/Vax1^tm1Grl involves: 129S1/Sv * C57BL/6	abnormal axon guidance	J:58996
	abnormal ependyma morphology	J:96805
	abnormal eye development	J:58996
	abnormal lateral ganglionic eminence morphology	J:96805
	abnormal neuron differentiation	J:96805
	abnormal olfactory bulb development	J:96805
	abnormal olfactory bulb morphology	J:96805
	abnormal optic nerve innervation	J:58996
	abnormal optic nerve morphology	J:58996
	abnormal postnatal subventricular zone morphology	J:96805
	abnormal rostral migratory stream morphology	J:96805
	absent corpus callosum	J:58996
	cleft palate	J:58996
	coloboma	J:58996
	neonatal lethality, incomplete penetrance	J:58996
Vax1^tm1Pgr/Vax1^tm1Pgr either: (involves: 129S1/Sv * 129X1/SvJ * C57BL/6) or (involves: 129S1/Sv * 129X1/SvJ * NMRI)	abnormal anterior commissure morphology	J:58997
	abnormal corpus callosum morphology	J:58997
	abnormal forebrain development	J:58997
	abnormal hypothalamus morphology	J:58997
	abnormal optic nerve innervation	J:58997
	abnormal optic nerve morphology	J:58997
	abnormal telencephalon development	J:58997
	abnormal upper incisor morphology	J:58997
	absent optic chiasm	J:58997
	cleft palate	J:58997
	coloboma	J:58997
	fused upper incisors	J:58997
	holoprosencephaly	J:58997
	lethality at weaning, incomplete penetrance	J:58997
	perinatal lethality, incomplete penetrance	J:58997
	premature death	J:58997
Vax1^tm1Pgr/Vax1^tm1Pgr involves: 129S1/Sv * 129X1/SvJ * C57BL/6	abnormal cranium morphology	J:257247
	abnormal frontonasal mesenchyme morphology	J:257247
	abnormal lateral ventricle morphology	J:257247
	abnormal maxilla morphology	J:257247
	abnormal midface morphology	J:257247
	abnormal nasal cavity morphology	J:257247
	abnormal pituitary gland morphology	J:257247
	abnormal premaxilla morphology	J:257247
	abnormal presphenoid bone morphology	J:257247
	abnormal upper incisor morphology	J:257247
	abnormal vomeronasal cartilage morphology	J:257247
	absent nasal septum	J:257247
	absent palatine bone horizontal plate	J:257247
	absent presphenoid bone	J:257247
	cleft palate	J:257247
	decreased forebrain size	J:257247
	lobar holoprosencephaly	J:257247
	maxillary retrognathia	J:257247
	maxillary shelf hypoplasia	J:257247
	midface hypoplasia	J:257247
	palatal shelves fail to meet at midline	J:257247
	palatine bone hypoplasia	J:257247
	presphenoid bone hypoplasia	J:257247
	small cranium	J:257247
	small mandible	J:257247
	vomer bone hypoplasia	J:257247

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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