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Mammalian Phenotype Ontology Annotations
Query Results - Summary
Symbol
Name
ID 		Dcx
doublecortin
MGI:1277171
43 phenotypes from multigenic genotypes
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Allelic Composition
Genetic Background		 Annotated Term Reference
Dclk1tm1.1Jgg/Dclk1+
Dcxtm1Caw/Y
involves: 129S1/Sv * 129X1/SvJ * Black Swiss * C57BL/6 		abnormal corpus callosum morphology J:105300
abnormal neuron morphology J:105300
decreased anterior commissure size J:105300
Dclk1tm1.1Jgg/Dclk1+
Dcxtm1Caw/Dcxtm1Caw
involves: 129S1/Sv * 129X1/SvJ * Black Swiss * C57BL/6 		absent corpus callosum J:105300
Dclk1tm1.1Jgg/Dclk1tm1.1Jgg
Dcxtm1Caw/Y
involves: 129S1/Sv * 129X1/SvJ * Black Swiss * C57BL/6 		abnormal anterior commissure morphology J:105300
abnormal stratification in cerebral cortex J:105300
absent corpus callosum J:105300
postnatal lethality, complete penetrance J:105300
Dclk1tm1.1Jgg/Dclk1tm1.1Jgg
Dcxtm1Caw/Dcx+
involves: 129S1/Sv * 129X1/SvJ * Black Swiss * C57BL/6 		abnormal anterior commissure morphology J:105300
abnormal stratification in cerebral cortex J:105300
absent corpus callosum J:105300
Dclk1tm1.1Jgg/Dclk1tm1.1Jgg
Dcxtm1Caw/Dcxtm1Caw
involves: 129S1/Sv * 129X1/SvJ * Black Swiss * C57BL/6 		abnormal brain commissure morphology J:105300
abnormal neuron morphology J:105300
abnormal stratification in cerebral cortex J:105300
absent anterior commissure J:105300
absent corpus callosum J:105300
absent hippocampal commissure J:105300
postnatal lethality, complete penetrance J:105300
Dclk1tm1Caw/Dclk1+
Dcxtm1Caw/Dcx+
involves: 129S6/SvEvTac * 129X1/SvJ * C57BL/6J 		reduced female fertility J:105301
Dclk1tm1Caw/Dclk1+
Dcxtm1Caw/Y
involves: 129S6/SvEvTac * 129X1/SvJ * C57BL/6J 		abnormal brain morphology J:105301
absent corpus callosum J:105301
enlarged lateral ventricles J:105301
postnatal lethality J:105301
Dclk1tm1Caw/Dclk1tm1Caw
Dcxtm1Caw/Y
involves: 129S6/SvEvTac * 129X1/SvJ * C57BL/6J 		abnormal anterior commissure morphology J:105301
abnormal brain internal capsule morphology J:105301
abnormal brain morphology J:105301
abnormal brainstem morphology J:105301
abnormal cerebellar foliation J:105301
abnormal cerebral cortex morphology J:105301
abnormal corpus callosum morphology J:105301
abnormal dentate gyrus morphology J:105301
abnormal entorhinal cortex morphology J:105301
abnormal hippocampal commissure morphology J:105301
abnormal hippocampus layer morphology J:105301
abnormal hippocampus morphology J:105301
abnormal stratification in cerebral cortex J:105301
abnormal striatum morphology J:105301
abnormal temporal lobe morphology J:105301
abnormal thalamus morphology J:105301
absent brain internal capsule J:105301
decreased corpus callosum size J:105301
postnatal lethality, incomplete penetrance J:105301
small cerebellum J:105301
thin cerebral cortex J:105301
Dclk1tm1Caw/Dclk1tm1Caw
Dcxtm1Caw/Dcx+
involves: 129S6/SvEvTac * 129X1/SvJ * C57BL/6J 		reduced female fertility J:105301
Dclk2tm1.2Jgg/Dclk2tm1.2Jgg
Dcxtm1Caw/Y
involves: 129/Sv * C57BL/6 		abnormal brain interneuron morphology J:148345
abnormal dentate gyrus morphology J:148345
abnormal hippocampal mossy fiber morphology J:148345
abnormal hippocampus CA1 region morphology J:148345
abnormal hippocampus CA3 region morphology J:148345
abnormal hippocampus granule cell layer J:148345
abnormal hippocampus pyramidal cell morphology J:148345
abnormal hippocampus region morphology J:148345
abnormal inhibitory postsynaptic currents J:148345
convulsive seizures J:148345
postnatal lethality, incomplete penetrance J:148345
premature death J:148345
tonic-clonic seizures J:148345
Dclk2tm1.2Jgg/Dclk2tm1.2Jgg
Dcxtm1Caw/Dcxtm1Caw
involves: 129/Sv * C57BL/6 		abnormal brain interneuron morphology J:148345
abnormal dentate gyrus morphology J:148345
abnormal hippocampal mossy fiber morphology J:148345
abnormal hippocampus CA1 region morphology J:148345
abnormal hippocampus CA3 region morphology J:148345
abnormal hippocampus granule cell layer J:148345
abnormal hippocampus pyramidal cell morphology J:148345
abnormal hippocampus region morphology J:148345
abnormal inhibitory postsynaptic currents J:148345
convulsive seizures J:148345
postnatal lethality, incomplete penetrance J:148345
premature death J:148345
tonic-clonic seizures J:148345
Dcxtm1(HBEGF)Pfba/?
involves: C57BL/6 		loss of hippocampal neurons J:196669
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Send questions and comments to User Support. 		last database update
11/19/2024
MGI 6.24 		The Jackson Laboratory