G6pc2 Phenotype Annotations

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Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

G6pc2
glucose-6-phosphatase, catalytic, 2
MGI:1277193

15 phenotypes from 3 alleles in 3 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
G6pc2^tm1.1Pesa/G6pc2^tm1.1Pesa NOD.129S2-G6pc2^tm1.1Pesa	abnormal CD8-positive, alpha beta T cell morphology	J:160286
	abnormal CD8-positive, alpha-beta T cell physiology	J:160286
	decreased interferon-gamma secretion	J:160286
	decreased T cell proliferation	J:160286
	normal immune system phenotype	J:160286
G6pc2^tm1Lex/G6pc2^tm1Lex involves: 129S5/SvEvBrd * C57BL/6	normal behavior/neurological phenotype	J:141593
	decreased circulating glucose level	J:141593
	decreased circulating triglyceride level	J:141593
	normal endocrine/exocrine gland phenotype	J:141593
	normal reproductive system phenotype	J:141593
Tg(H2-Ea-G6pc2)69Tkay/? NOD-Tg(H2-Ea-G6pc2)69Tkay	abnormal CD4-positive, alpha-beta T cell physiology	J:117352
	abnormal CD8-positive, alpha beta T cell morphology	J:117352
	abnormal immune tolerance	J:117352
	decreased T cell proliferation	J:117352
	increased anti-insulin autoantibody level	J:117352
	increased susceptibility to autoimmune diabetes	J:117352
	insulitis	J:117352

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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