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Mammalian Phenotype Ontology Annotations
Query Results - Summary
Symbol
Name
ID 		G6pc2
glucose-6-phosphatase, catalytic, 2
MGI:1277193
15 phenotypes from 3 alleles in 3 genetic backgrounds
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Allelic Composition
Genetic Background		 Annotated Term Reference
G6pc2tm1.1Pesa/G6pc2tm1.1Pesa
NOD.129S2-G6pc2tm1.1Pesa 		abnormal CD8-positive, alpha beta T cell morphology J:160286
abnormal CD8-positive, alpha-beta T cell physiology J:160286
decreased interferon-gamma secretion J:160286
decreased T cell proliferation J:160286
normal immune system phenotype J:160286
G6pc2tm1Lex/G6pc2tm1Lex
involves: 129S5/SvEvBrd * C57BL/6 		normal behavior/neurological phenotype J:141593
decreased circulating glucose level J:141593
decreased circulating triglyceride level J:141593
normal endocrine/exocrine gland phenotype J:141593
normal reproductive system phenotype J:141593
Tg(H2-Ea-G6pc2)69Tkay/?
NOD-Tg(H2-Ea-G6pc2)69Tkay 		abnormal CD4-positive, alpha-beta T cell physiology J:117352
abnormal CD8-positive, alpha beta T cell morphology J:117352
abnormal immune tolerance J:117352
decreased T cell proliferation J:117352
increased anti-insulin autoantibody level J:117352
increased susceptibility to autoimmune diabetes J:117352
insulitis J:117352
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
12/10/2024
MGI 6.24 		The Jackson Laboratory