Cxcr3 Phenotype Annotations

Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Cxcr3
C-X-C motif chemokine receptor 3
MGI:1277207

17 phenotypes from 4 alleles in 5 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Cxcr3^tm1Arsa/Y involves: 129S4/SvJae	no abnormal phenotype detected	J:193492
Cxcr3^tm1Dgen/Y involves: 129P2/OlaHsd * C57BL/6	increased circulating glucose level	J:101679
Cxcr3^tm1Raks/Cxcr3^tm1Raks B6.129P2-Cxcr3^tm1Raks	albuminuria	J:152790
	decreased blood urea nitrogen level	J:152790
	decreased circulating creatinine level	J:152790
	decreased susceptibility to injury	J:152790
	kidney inflammation	J:152790
Cxcr3^tm1Wwh/Y B6.Cg-Cxcr3^tm1Wwh	abnormal cellular extravasation	J:107646
	abnormal interferon level	J:91359
	abnormal physiological neovascularization	J:107646
	impaired macrophage chemotaxis	J:107646
	increased length of allograft survival	J:65916
	lung inflammation	J:91359
	pulmonary interstitial fibrosis	J:91359
Cxcr3^tm1Wwh/Cxcr3^tm1Wwh B6.Cg-Cxcr3^tm1Wwh	abnormal cellular extravasation	J:96905, J:107646
	abnormal interferon level	J:91359
	abnormal physiological neovascularization	J:107646
	decreased susceptibility to Riboviria infection	J:96905
	decreased susceptibility to Riboviria infection induced morbidity/mortality	J:96905
	impaired macrophage chemotaxis	J:107646
	increased length of allograft survival	J:65916
	lung inflammation	J:91359
	pulmonary interstitial fibrosis	J:91359
Cxcr3^tm1Wwh/Cxcr3^tm1Wwh Not Specified	increased tumor incidence	J:163822

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources Funding Information Warranty Disclaimer, Privacy Notice, Licensing, & Copyright Send questions and comments to User Support.	last database update 11/12/2024 MGI 6.24