Rpap3 Phenotype Annotations

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Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Rpap3
RNA polymerase II associated protein 3
MGI:1277218

17 phenotypes from 2 alleles in 3 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Rpap3^em1(IMPC)Mbp/Rpap3⁺ C57BL/6N-Rpap3^em1(IMPC)Mbp/Ucd	abnormal testis morphology	J:211773
	abnormal thymus morphology	J:211773
	decreased circulating calcium level	J:211773
	decreased circulating glucose level	J:211773
	decreased circulating phosphate level	J:211773
	enlarged thymus	J:211773
	small testis	J:211773
Rpap3^em1(IMPC)Mbp/Rpap3^em1(IMPC)Mbp C57BL/6N-Rpap3^em1(IMPC)Mbp/Ucd	embryonic lethality prior to organogenesis	J:211773
	preweaning lethality, complete penetrance	J:211773
Rpap3^{tm1c(KOMP)Wtsi}/Rpap3^{tm1c(KOMP)Wtsi} Lgr5^{tm1(cre/ERT2)Cle}/Lgr5⁺ involves: 129P2/OlaHsd * C57BL/6N	no abnormal phenotype detected	J:314346
Rpap3^{tm1c(KOMP)Wtsi}/Rpap3^{tm1c(KOMP)Wtsi} Tg(Vil1-cre/ERT2)23Syr/0 involves: C57BL/6N * DBA/2	abnormal enterocyte morphology	J:314346
	abnormal intestinal epithelium physiology	J:314346
	abnormal small intestine goblet cell morphology	J:314346
	abnormal small intestine morphology	J:314346
	decreased small intestine length	J:314346
	small intestinal inflammation	J:314346
	weight loss	J:314346

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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