Ccdc86 Phenotype Annotations - Multigenic Genotypes

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Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Ccdc86
coiled-coil domain containing 86
MGI:1277220

7 phenotypes from multigenic genotypes

Allelic Composition Genetic Background	Annotated Term	Reference
Fas^lpr/Fas^lpr Il2ra^tm1Dw/Il2ra^tm1Dw Tg(CD2-Ccdc86)1Hfuj/? B6.Cg-Il2ra^tm1Dw Fas^lpr Tg(CD2-Ccdc86)1Hfuj	enlarged spleen	J:151722
Il2ra^tm1Dw/Il2ra^tm1Dw Tg(CD2-Ccdc86)1Hfuj/? B6.Cg-Il2ra^tm1Dw Tg(CD2-Ccdc86)1Hfuj	normal immune system phenotype	J:151722
	increased activated T cell number	J:151722
Il2rg^tm1Wjl/Il2rg^tm1Wjl Tg(CD2-Ccdc86)1Hfuj/? B6.Cg-Il2rg^tm1Wjl Tg(CD2-Ccdc86)1Hfuj	decreased CD4-positive, alpha-beta T cell number	J:151722
	decreased CD8-positive, alpha-beta T cell number	J:151722
	decreased regulatory T cell number	J:151722
	decreased splenocyte number	J:151722
	normal immune system phenotype	J:151722

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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