Atxn2 Phenotype Annotations

Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Atxn2
ataxin 2
MGI:1277223

24 phenotypes from 3 alleles in 3 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Atxn2^tm1.1Aub/Atxn2^tm1.1Aub involves: 129P2/OlaHsd * C57BL/6	abnormal lipid level	J:135320
	decreased circulating glucose level	J:135320
	decreased litter size	J:135320
	hepatic steatosis	J:135320
	hyperactivity	J:135320
	increased circulating cholesterol level	J:135320
	increased circulating insulin level	J:135320
	increased gonadal fat pad weight	J:135320
	increased insulin secretion	J:135320
	increased liver glycogen level	J:135320
	increased pancreatic beta cell number	J:135320
	increased susceptibility to weight gain	J:135320
	pancreatic islet hyperplasia	J:135320
	prenatal lethality, incomplete penetrance	J:135320
	reduced fertility	J:135320
Atxn2^tm1Plt/Atxn2^tm1Plt involves: 129X1/SvJ * C57BL/6	abnormal abdominal fat pad morphology	J:103805
	normal behavior/neurological phenotype	J:103805
	enlarged seminal vesicle	J:103805
	hepatic steatosis	J:103805
	impaired coordination	J:103805
	increased body weight	J:103805
	intrahepatic cholestasis	J:103805
	normal nervous system phenotype	J:103805
Atxn2^tm2.1Aub/Atxn2^tm2.1Aub B6.129S2-Atxn2^tm2.1Aub	abnormal Purkinje cell morphology	J:188118
	normal behavior/neurological phenotype	J:188118
	decreased body weight	J:188118
	impaired coordination	J:188118

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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