Fhit Phenotype Annotations

Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Fhit
fragile histidine triad gene
MGI:1277947

11 phenotypes from 2 alleles in 2 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Fhit^tm1Hbn/Fhit⁺ involves: 129X1/SvJ * C57BL/6	alopecia	J:110096
	decreased granulocyte number	J:71303
	increased incidence of tumors by chemical induction	J:61946, J:71303, J:110096
	increased susceptibility to infection	J:71303
	increased tumor incidence	J:71303
	premature death	J:71303
Fhit^tm1Hbn/Fhit^tm1Hbn involves: 129X1/SvJ * C57BL/6	decreased granulocyte number	J:71303
	increased incidence of tumors by chemical induction	J:71303
	increased susceptibility to infection	J:71303
	increased tumor incidence	J:71303
	premature death	J:71303
Fhit^tm1Tko/Fhit⁺ involves: 129X1/SvJ	abnormal small intestine morphology	J:93269
	increased B cell derived lymphoma incidence	J:93269
	increased lymphoma incidence	J:93269
	increased papilloma incidence	J:93269
Fhit^tm1Tko/Fhit^tm1Tko involves: 129X1/SvJ	abnormal small intestine morphology	J:93269
	increased B cell derived lymphoma incidence	J:93269
	increased hepatocellular carcinoma incidence	J:93269
	increased lymphoma incidence	J:93269
	increased papilloma incidence	J:93269

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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