Casp9 Phenotype Annotations

Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Casp9
caspase 9
MGI:1277950

42 phenotypes from 2 alleles in 3 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Casp9^tm1Flv/Casp9^tm1Flv B6.129S1-Casp9^tm1Flv	abnormal apoptosis	J:65496
Casp9^tm1Flv/Casp9^tm1Flv involves: 129S1/Sv * C57BL/6	abnormal apoptosis	J:66953, J:103480
	abnormal brain development	J:49088
	abnormal brain morphology	J:90572
	abnormal cerebral cortex morphology	J:90572
	abnormal embryonic neuroepithelial layer differentiation	J:49088
	abnormal forebrain development	J:49088
	abnormal lamina terminalis morphology	J:49088
	abnormal lateral ventricle morphology	J:49088
	abnormal midbrain-hindbrain boundary morphology	J:49088
	abnormal neural tube closure	J:49088
	abnormal olfactory epithelium morphology	J:90572
	abnormal telencephalon development	J:49088
	abnormal telencephalon morphology	J:49088
	abnormal third ventricle morphology	J:49088
	abnormal thymocyte apoptosis	J:49088
	brain ventricle stenosis	J:49088
	normal cellular phenotype	J:49088
	decreased neuron apoptosis	J:49088, J:90572
	decreased T cell apoptosis	J:91156
	normal embryo phenotype	J:49088
	exencephaly	J:49088
	normal hematopoietic system phenotype	J:91156
	normal immune system phenotype	J:49088
	increased midbrain size	J:49088
	perinatal lethality	J:90572
	perinatal lethality, incomplete penetrance	J:49088
Casp9^tm1Mak/Casp9^tm1Mak either: (involves: 129P2/OlaHsd * C57BL/6J) or (involves: 129P2/OlaHsd * CD-1)	abnormal brain commissure morphology	J:49087
	abnormal brain ventricle morphology	J:49087
	abnormal cell physiology	J:49087
	abnormal cerebral cortex morphology	J:49087
	abnormal cerebral hemisphere morphology	J:49087
	abnormal forebrain development	J:49087
	abnormal lateral ventricle morphology	J:49087
	abnormal respiratory electron transport chain	J:49087
	abnormal splenocyte apoptosis	J:49087
	abnormal thymocyte apoptosis	J:49087
	absent corpus callosum	J:49087
	decreased apoptosis	J:49087
	decreased birth body size	J:49087
	decreased body size	J:49087
	decreased cellular sensitivity to gamma-irradiation	J:49087
	decreased neuron apoptosis	J:49087
	decreased sensitivity to induced cell death	J:49087
	hydrocephaly	J:49087
	normal immune system phenotype	J:49087
	intracerebral hemorrhage	J:49087
	postnatal lethality, incomplete penetrance	J:49087
	prenatal lethality, incomplete penetrance	J:49087

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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