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Mammalian Phenotype Ontology Annotations
Query Results - Summary
Symbol
Name
ID 		Casp9
caspase 9
MGI:1277950
42 phenotypes from 2 alleles in 3 genetic backgrounds
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Allelic Composition
Genetic Background		 Annotated Term Reference
Casp9tm1Flv/Casp9tm1Flv
B6.129S1-Casp9tm1Flv 		abnormal apoptosis J:65496
Casp9tm1Flv/Casp9tm1Flv
involves: 129S1/Sv * C57BL/6 		abnormal apoptosis J:66953, J:103480
abnormal brain development J:49088
abnormal brain morphology J:90572
abnormal cerebral cortex morphology J:90572
abnormal embryonic neuroepithelial layer differentiation J:49088
abnormal forebrain development J:49088
abnormal lamina terminalis morphology J:49088
abnormal lateral ventricle morphology J:49088
abnormal midbrain-hindbrain boundary morphology J:49088
abnormal neural tube closure J:49088
abnormal olfactory epithelium morphology J:90572
abnormal telencephalon development J:49088
abnormal telencephalon morphology J:49088
abnormal third ventricle morphology J:49088
abnormal thymocyte apoptosis J:49088
brain ventricle stenosis J:49088
normal cellular phenotype J:49088
decreased neuron apoptosis J:49088, J:90572
decreased T cell apoptosis J:91156
normal embryo phenotype J:49088
exencephaly J:49088
normal hematopoietic system phenotype J:91156
normal immune system phenotype J:49088
increased midbrain size J:49088
perinatal lethality J:90572
perinatal lethality, incomplete penetrance J:49088
Casp9tm1Mak/Casp9tm1Mak
either: (involves: 129P2/OlaHsd * C57BL/6J) or (involves: 129P2/OlaHsd * CD-1) 		abnormal brain commissure morphology J:49087
abnormal brain ventricle morphology J:49087
abnormal cell physiology J:49087
abnormal cerebral cortex morphology J:49087
abnormal cerebral hemisphere morphology J:49087
abnormal forebrain development J:49087
abnormal lateral ventricle morphology J:49087
abnormal respiratory electron transport chain J:49087
abnormal splenocyte apoptosis J:49087
abnormal thymocyte apoptosis J:49087
absent corpus callosum J:49087
decreased apoptosis J:49087
decreased birth body size J:49087
decreased body size J:49087
decreased cellular sensitivity to gamma-irradiation J:49087
decreased neuron apoptosis J:49087
decreased sensitivity to induced cell death J:49087
hydrocephaly J:49087
normal immune system phenotype J:49087
intracerebral hemorrhage J:49087
postnatal lethality, incomplete penetrance J:49087
prenatal lethality, incomplete penetrance J:49087
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
11/12/2024
MGI 6.24 		The Jackson Laboratory