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Mammalian Phenotype Ontology Annotations
Query Results - Summary
Symbol
Name
ID 		Kcnn4
potassium intermediate/small conductance calcium-activated channel, subfamily N, member 4
MGI:1277957
46 phenotypes from 4 alleles in 5 genetic backgrounds
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Allelic Composition
Genetic Background		 Annotated Term Reference
Kcnn4em1(IMPC)Ccpcz/Kcnn4em1(IMPC)Ccpcz
C57BL/6NCrl-Kcnn4em1(IMPC)Ccpcz/Ccpcz 		abnormal colon morphology J:211773
abnormal digit morphology J:211773
abnormal heart morphology J:211773
abnormal joint morphology J:211773
abnormal liver morphology J:211773
abnormal rectum morphology J:211773
abnormal seminal vesicle morphology J:211773
abnormal skin morphology J:211773
abnormal spleen morphology J:211773
abnormal testis morphology J:211773
abnormal thymus morphology J:211773
abnormal tooth morphology J:211773
decreased exploration in new environment J:211773
enlarged cecum J:211773
enlarged spleen J:211773
enlarged testis J:211773
enlarged thymus J:211773
hydrometra J:211773
increased fasting circulating glucose level J:211773
increased freezing behavior J:211773
increased red blood cell distribution width J:211773
small heart J:211773
small liver J:211773
small seminal vesicle J:211773
small thymus J:211773
Kcnn4tm1.1Jele/Kcnn4tm1.1Jele
either: (involves: 129S1/Sv * 129X1/SvJ) or (involves: 129S1/Sv * 129X1/SvJ * C57BL/6) 		abnormal digestive system physiology J:135743
Kcnn4tm1Jemn/Kcnn4tm1Jemn
involves: 129S1/Sv * C57BL/6J 		abnormal hematopoietic system physiology J:94478
abnormal T cell physiology J:94478
increased parotid gland size J:94478
Kcnn4tm1Rklr/Kcnn4tm1Rklr
B6.129S-Kcnn4tm1Rklr 		decreased susceptibility to injury J:151989
renal interstitial fibrosis J:151989
Kcnn4tm1Rklr/Kcnn4tm1Rklr
involves: 129S/SvEv * C57BL/6 		abnormal heart left ventricle morphology J:124858
abnormal heart morphology J:124858
abnormal red blood cell deformability J:148910
abnormal systemic arterial blood pressure J:124858
decreased vasodilation J:124858
enlarged spleen J:148910
increased erythrocyte osmotic fragility J:148910
increased heart weight J:124858
increased hematocrit J:148910
increased hemoglobin concentration distribution width J:148910
increased mean corpuscular volume J:148910
increased mean systemic arterial blood pressure J:124858
increased spleen iron level J:148910
increased spleen weight J:148910
increased systemic arterial diastolic blood pressure J:124858
increased systemic arterial systolic blood pressure J:124858
macrocytosis J:148910
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
12/10/2024
MGI 6.24 		The Jackson Laboratory