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Mammalian Phenotype Ontology Annotations
Query Results - Summary
Symbol
Name
ID 		Plec
plectin
MGI:1277961
54 phenotypes from 11 alleles in 12 genetic backgrounds
Export: Excel File
Allelic Composition
Genetic Background		 Annotated Term Reference
Plec/Parp10tm1.1Gwi/Plec/Parp10tm1.1Gwi
involves: BALB/cJ * C57BL/6 		abnormal axon morphology J:155511
normal behavior/neurological phenotype J:155511
decreased nerve conduction velocity J:155511
Plecem1(IMPC)Bay/Plecem1(IMPC)Bay
C57BL/6N-Plecem1(IMPC)Bay/BayMmucd 		edema J:211773
preweaning lethality, complete penetrance J:211773
PlecGt(U3Betageo)1Ruiz/PlecGt(U3Betageo)1Ruiz
involves: 129S2/SvPas * C57BL/6 		prenatal lethality, complete penetrance J:85162
Plectm1Gwi/Plectm1Gwi
involves: 129S1/Sv * 129X1/SvJ 		abnormal dermal layer morphology J:59000
abnormal epidermis stratum basale morphology J:59000
abnormal intercalated disk morphology J:59000
abnormal keratinocyte morphology J:59000
abnormal myocardial fiber morphology J:59000
abnormal skeletal muscle fiber morphology J:59000
absent epidermis stratum basale J:59000
blistering J:59000
decreased body weight J:59000
hemorrhage J:59000
muscle degeneration J:59000
myopathy J:59000
postnatal lethality, complete penetrance J:59000
skin detachment J:59000
Plectm1Gwi/Plectm4Gwi
Tg(Ckmm-cre)5Khn/?
involves: 129P2/OlaHsd * 129S1/Sv * 129X1/SvJ * C57BL/6J * FVB 		abnormal heart morphology J:137067
abnormal muscle fiber mitochondrial morphology J:137067
abnormal myocardial fiber morphology J:137067
abnormal sarcolemma morphology J:137067
abnormal skeletal muscle fiber morphology J:137067
abnormal soleus morphology J:137067
normal cardiovascular system phenotype J:137067
centrally nucleated skeletal muscle fibers J:137067
decreased skeletal muscle fiber number J:137067
decreased skeletal muscle mass J:137067
decreased survivor rate J:137067
impaired exercise endurance J:137067
increased skeletal muscle fiber size J:137067
normal muscle phenotype J:137067
skeletal muscle fiber atrophy J:137067
skeletal muscle fiber necrosis J:137067
Plectm2Gwi/Plectm2Gwi
involves: 129S1/Sv * 129X1/SvJ 		abnormal dermal layer morphology J:59000
abnormal epidermis stratum basale morphology J:59000
abnormal intercalated disk morphology J:59000
abnormal keratinocyte morphology J:59000
abnormal myocardial fiber morphology J:59000
abnormal skeletal muscle fiber morphology J:59000
absent epidermis stratum basale J:59000
blistering J:59000
decreased body weight J:59000
hemorrhage J:59000
muscle degeneration J:59000
myopathy J:59000
postnatal lethality, complete penetrance J:59000
skin detachment J:59000
Plectm2Gwi/Plectm4Gwi
Tg(Krt1-5-cre/ERT)1Ipc/?
involves: 129 * C57BL/6 * SJL 		abnormal skin condition J:124213
blistering J:124213
impaired skin barrier function J:124213
Plectm3Gwi/Plectm3Gwi
involves: 129P2/OlaHsd 		abnormal cell morphology J:104701
abnormal T cell physiology J:104701
abnormal wound healing J:104701
decreased fibroblast cell migration J:104701
decreased fibroblast chemotaxis J:104701
impaired macrophage chemotaxis J:104701
impaired wound healing J:104701
normal integument phenotype J:104701
normal muscle phenotype J:137067
Plectm4Gwi/Plectm4.1Gwi
Tg(Nes-cre)1Kln/0
involves: 129P2/OlaHsd * BALB/cJ * C57BL/6 * SJL 		decreased nerve conduction velocity J:155511
Plectm4Gwi/Plectm4Gwi
involves: 129P2/OlaHsd * C57BL/6 		no abnormal phenotype detected J:124213
Plectm4Gwi/Plectm4Gwi
Tg(Ckmm-cre)5Khn/?
involves: 129P2/OlaHsd * C57BL/6J * FVB 		abnormal heart morphology J:137067
abnormal muscle fiber mitochondrial morphology J:137067
abnormal myocardial fiber morphology J:137067
abnormal sarcolemma morphology J:137067
abnormal skeletal muscle fiber morphology J:137067
abnormal soleus morphology J:137067
normal cardiovascular system phenotype J:137067
centrally nucleated skeletal muscle fibers J:137067
decreased skeletal muscle fiber number J:137067
decreased skeletal muscle mass J:137067
decreased survivor rate J:137067
impaired exercise endurance J:137067
increased skeletal muscle fiber size J:137067
normal muscle phenotype J:137067
skeletal muscle fiber atrophy J:137067
skeletal muscle fiber necrosis J:137067
Plectm4Gwi/Plectm4Gwi
Tg(KRT5-cre)1Tak/?
involves: 129P2/OlaHsd * C3H * C57BL/6 		abnormal skin condition J:124213
abnormal suckling behavior J:124213
blistering J:124213
decreased body size J:124213
impaired skin barrier function J:124213
postnatal growth retardation J:124213
postnatal lethality, complete penetrance J:124213
skin lesions J:124213
Plectm5Gwi/Plectm5Gwi
involves: 129P2/OlaHsd * C57BL/6 		abnormal aerobic respiration J:137067
abnormal skeletal muscle fiber morphology J:137067
centrally nucleated skeletal muscle fibers J:137067
decreased skeletal muscle fiber diameter J:137067
increased skeletal muscle fiber size J:137067
skeletal muscle fiber necrosis J:137067
Plectm6Gwi/Plectm6Gwi
Not Specified 		normal muscle phenotype J:137067
Plectm7.1Gwi/Plec+
involves: 129P2/OlaHsd * C57BL/6 		abnormal keratinocyte morphology J:179812
abnormal keratinocyte physiology J:179812
abnormal skin exfoliation J:179812
dermal-epidermal separation J:179812
skin lesions J:179812
Plectm7.1Gwi/Plectm7.1Gwi
involves: 129P2/OlaHsd * C57BL/6 		abnormal keratinocyte morphology J:179812
abnormal skin exfoliation J:179812
dermal-epidermal separation J:179812
skin lesions J:179812
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
12/10/2024
MGI 6.24 		The Jackson Laboratory