Cavin1 Phenotype Annotations

Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Cavin1
caveolae associated 1
MGI:1277968

25 phenotypes from 1 allele in 2 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Cavin1^tm1Pfp/Cavin1^tm1Pfp B6.129S6-Cavin1^tm1Pfp/J	abnormal lung morphology	J:217258
	abnormal lung vasculature morphology	J:217258
	abnormal urinary bladder detrusor smooth muscle morphology	J:217273
	absent caveolae	J:217258, J:217273
	impaired contractility of urinary bladder detrusor smooth muscle	J:217273
	increased heart right ventricle weight	J:217258
	increased right ventricle systolic pressure	J:217258
	increased urinary bladder weight	J:217273
	perinatal lethality, incomplete penetrance	J:217273
	prenatal lethality, incomplete penetrance	J:217273
	pulmonary hypertension	J:217258
Cavin1^tm1Pfp/Cavin1^tm1Pfp involves: 129S6/SvEvTac * C57BL/6	abnormal circulating hormone level	J:143425
	abnormal circulating lipid level	J:143425
	abnormal lung vasculature morphology	J:205741
	abnormal vascular endothelial cell morphology	J:205741
	absent caveolae	J:143425, J:205741
	decreased basal metabolism	J:143425
	decreased circulating leptin level	J:143425
	decreased locomotor activity	J:143425
	hyperlipidemia	J:143425
	impaired glucose tolerance	J:143425
	increased circulating free fatty acids level	J:143425
	increased circulating insulin level	J:143425
	increased circulating triglyceride level	J:143425
	increased lean body mass	J:143425
	insulin resistance	J:143425
	preweaning lethality, incomplete penetrance	J:205741

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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