Fgf18 Phenotype Annotations

Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Fgf18
fibroblast growth factor 18
MGI:1277980

45 phenotypes from 3 alleles in 4 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Fgf18^tm1Dor/Fgf18^tm1Dor involves: 129X1/SvJ * C57BL/6J	abnormal axial skeleton morphology	J:75879
	abnormal cranial suture morphology	J:75879
	abnormal craniofacial bone morphology	J:75879
	abnormal fibula morphology	J:75879
	abnormal limb bone morphology	J:75879
	abnormal limb morphology	J:75879
	abnormal long bone epiphyseal plate proliferative zone	J:75879
	abnormal metatarsal bone morphology	J:75879
	abnormal neurocranium morphology	J:75879
	abnormal osteoblast differentiation	J:75879
	abnormal respiratory mechanics	J:75879
	abnormal rib morphology	J:75879
	abnormal skeleton development	J:75879
	bowed radius	J:75879
	bowed tibia	J:75879
	cleft secondary palate	J:75879
	cyanosis	J:75879
	decreased birth body size	J:75879
	delayed bone ossification	J:75879
	delayed endochondral bone ossification	J:75879
	delayed intramembranous bone ossification	J:75879
	failure of palatal shelf elevation	J:75879
	increased long bone epiphyseal plate size	J:75879
	increased width of hypertrophic chondrocyte zone	J:75879
	maxilla hypoplasia	J:75879
	neonatal lethality, complete penetrance	J:75879
	small neurocranium	J:75879
	small thoracic cavity	J:75879
Fgf18^tm1Sjt/Fgf18^tm1Sjt B6.129S1-Fgf18^tm1Sjt	abnormal rib morphology	J:157157
Fgf18^tm1Sjt/Fgf18^tm1Sjt B6.129S1-Fgf18^tm1Sjt	neonatal lethality, complete penetrance	J:157157
Fgf18^tm1Sjt/Fgf18^tm1Sjt involves: 129S1/Sv * C57BL/6	abnormal fibula morphology	J:75880
	abnormal lung development	J:91986
	abnormal lung saccule morphology	J:91986
	abnormal lung vasculature morphology	J:91986
	abnormal rib morphology	J:75880
	delayed bone ossification	J:75880
	delayed cranial suture closure	J:75880
	kyphosis	J:75880
	perinatal lethality, complete penetrance	J:75880
	short radius	J:75880
	short tibia	J:75880
	short ulna	J:75880
	small lung	J:91986
	small lung lobe	J:91986
	small thoracic cavity	J:75880
	thick lung-associated mesenchyme	J:91986
Fgf18^tm1Tri/Fgf18^tm1Tri Tg(KRT5-cre)1Tak/0 involves: 129 * C3H * C57BL/6 * C57BL/6JJcl	abnormal coat appearance	J:184628
	abnormal hair cycle	J:184628
	abnormal hair cycle anagen phase	J:184628
	abnormal hair cycle telogen phase	J:184628
	normal integument phenotype	J:184628

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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