Dach1 Phenotype Annotations

Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Dach1
dachshund family transcription factor 1
MGI:1277991

14 phenotypes from 3 alleles in 4 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Dach1^{tm1b(KOMP)Wtsi}/Dach1⁺ B6N(Cg)-Dach1^{tm1b(KOMP)Wtsi}/J	increased circulating alanine transaminase level	J:211773
	increased circulating chloride level	J:211773
Dach1^{tm1b(KOMP)Wtsi}/Dach1^{tm1b(KOMP)Wtsi} B6N(Cg)-Dach1^{tm1b(KOMP)Wtsi}/J	preweaning lethality, complete penetrance	J:211773
Dach1^tm1Krs/Dach1^tm1Krs involves: 129P2/OlaHsd	absent gastric milk in neonates	J:81143
	cyanosis	J:81143
	decreased pancreatic alpha cell number	J:166952
	decreased pancreatic beta cell number	J:166952
	decreased pancreatic beta cell proliferation	J:166952
	normal endocrine/exocrine gland phenotype	J:166952
	neonatal lethality, complete penetrance	J:81143
	normal nervous system phenotype	J:81143
	respiratory distress	J:81143
	small pancreatic islets	J:166952
Dach1^tm1Mrd/Dach1^tm1Mrd involves: 129S7/SvEvBrd	abnormal suckling behavior	J:67361
	cyanosis	J:67361
	neonatal lethality, complete penetrance	J:67361
	respiratory distress	J:67361
Dach1^tm1Mrd/Dach1^tm1Mrd involves: 129S7/SvEvBrd * C57BL/6	abnormal suckling behavior	J:67361
	cyanosis	J:67361
	neonatal lethality, complete penetrance	J:67361
	respiratory distress	J:67361

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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