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Mammalian Phenotype Ontology Annotations
Query Results - Summary
Symbol
Name
ID 		Fpr2
formyl peptide receptor 2
MGI:1278319
35 phenotypes from 4 alleles in 6 genetic backgrounds
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Allelic Composition
Genetic Background		 Annotated Term Reference
Fpr2tm1.1Jimw/Fpr2tm1.1Jimw
Lyz2tm1(cre)Ifo/Lyz2+
involves: 129P2/OlaHsd * 129X1/SvJ 		decreased susceptibility to induced colitis J:197568
Fpr2tm1.1Jimw/Fpr2tm1.1Jimw
Tg(Vil1-cre)997Gum/0
involves: 129X1/SvJ * C57BL/6J * SJL 		abnormal large intestine crypts of Lieberkuhn morphology J:197568
Fpr2tm1.2Jimw/Fpr2tm1.2Jimw
B6.129X1-Fpr2tm1.2Jimw 		abnormal bone marrow cell physiology J:160074
abnormal cytokine secretion J:160074
abnormal dendritic cell physiology J:160074
abnormal innate immunity J:160074
decreased dendritic cell number J:160074
decreased IgE level J:160074
decreased IgG1 level J:160074
decreased IgG2b level J:160074
decreased immunoglobulin level J:160074
decreased inflammatory response J:160074
decreased interferon-gamma secretion J:160074
decreased interleukin-2 secretion J:160074
decreased interleukin-4 secretion J:160074
decreased interleukin-5 secretion J:160074
decreased interleukin-13 secretion J:160074
decreased respiratory mucosa goblet cell number J:160074
impaired macrophage chemotaxis J:160074
impaired neutrophil chemotaxis J:160074
small lymph nodes J:160074
Fpr2tm1.2Jimw/Fpr2tm1.2Jimw
involves: 129X1/SvJ 		abnormal colon morphology J:197568
abnormal dendritic cell chemotaxis J:199611
abnormal dendritic cell physiology J:199611
abnormal enterocyte proliferation J:197568
abnormal large intestine crypts of Lieberkuhn morphology J:197568
colitis J:197568
decreased acute inflammation J:197568
decreased dendritic cell number J:199611
increased colon adenoma incidence J:197568
increased incidence of tumors by chemical induction J:197568
increased susceptibility to xenobiotic induced morbidity/mortality J:197568
intestinal ulcer J:197568
Fpr2tm1Rjf/Fpr2tm1Rjf
involves: 129S/SvEv * C57BL/6 		abnormal neutrophil physiology J:159658
abnormal response to injury J:159658
impaired macrophage chemotaxis J:159658
increased acute inflammation J:159658
increased susceptibility to induced arthritis J:159658
Tg(ACTB-Fpr2)#Jimw/0
involves: FVB 		abnormal dendritic cell physiology J:160074
respiratory system inflammation J:160074
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
12/10/2024
MGI 6.24 		The Jackson Laboratory