Dgkz Phenotype Annotations

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Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Dgkz
diacylglycerol kinase zeta
MGI:1278339

18 phenotypes from 1 allele in 2 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Dgkz^tm1Gak/Dgkz^tm1Gak B6.129X1-Dgkz^tm1Gak	abnormal interleukin-2 secretion	J:113564
	abnormal lymphocyte anergy	J:113564
	increased T cell number	J:113564
Dgkz^tm1Gak/Dgkz^tm1Gak involves: 129X1/SvJ * C57BL/6	abnormal cytokine level	J:293120
	abnormal cytokine secretion	J:293120
	abnormal inflammatory response	J:293120
	abnormal interferon level	J:85149
	abnormal macrophage physiology	J:293120
	abnormal T cell activation	J:85149
	abnormal T cell physiology	J:85149
	decreased CD4-positive, alpha-beta T cell number	J:85149
	decreased CD8-positive, alpha-beta T cell number	J:85149
	decreased circulating ferritin level	J:293120
	decreased interleukin-6 secretion	J:293120
	decreased susceptibility to induced arthritis	J:293120
	decreased susceptibility to Riboviria infection	J:85149
	increased B cell number	J:85149
	increased T cell proliferation	J:85149

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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