Lect2 Phenotype Annotations - Multigenic Genotypes

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Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Lect2
leukocyte cell-derived chemotaxin 2
MGI:1278342

14 phenotypes from multigenic genotypes

Allelic Composition Genetic Background	Annotated Term	Reference
Apc^tm2.1Cip/Apc^tm2.1Cip Lect2^tm1Ymg/Lect2^tm1Ymg Tg(Ttr-cre/Esr1)1Vco/0 B6.Cg-Lect2^tm1Ymg Apc^tm2.1Cip Tg(Ttr-cre/Esr1)1Vco	abnormal chemokine level	J:184496
	abnormal circulating enzyme level	J:184496
	abnormal liver morphology	J:184496
	abnormal neutrophil physiology	J:184496
	abnormal NK T cell physiology	J:184496
	decreased interferon-gamma secretion	J:184496
	hepatic necrosis	J:184496
	increased hepatocyte apoptosis	J:184496
	increased interleukin-4 secretion	J:184496
	increased NK T cell number	J:184496
	liver inflammation	J:184496
	premature death	J:184496
Lect2^tm1Ymg/Lect2^tm1Ymg Tg(Pklr-Myc)73Ak/0 B6.Cg-Lect2^tm1Ymg Tg(Pklr-Myc)73Ak	increased hepatocellular carcinoma incidence	J:184496
	increased malignant tumor incidence	J:184496

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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