Scyl2 Phenotype Annotations

Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Scyl2
SCY1-like 2 (S. cerevisiae)
MGI:1289172

21 phenotypes from 2 alleles in 2 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Scyl2^tm1.1Spel/Scyl2^tm1.1Spel involves: 129S6/SvEvTac * C57BL/6	no abnormal phenotype detected	J:225808
Scyl2^tm1.1Spel/Scyl2^tm1.1Spel Tg(Nes-cre)1Kln/0 involves: 129S6/SvEvTac * C57BL/6 * SJL	abnormal behavior	J:225808
	abnormal depression-related behavior	J:225808
	abnormal excitatory postsynaptic potential	J:225808
	astrocytosis	J:225808
	decreased body weight	J:225808
	decreased brain size	J:225808
	decreased dentate gyrus size	J:225808
	decreased grip strength	J:225808
	decreased hippocampus pyramidal cell number	J:225808
	hippocampal neuron degeneration	J:225808
	increased neuron apoptosis	J:225808
	limb grasping	J:225808
	microgliosis	J:225808
	neonatal lethality, incomplete penetrance	J:225808
	postnatal growth retardation	J:225808
	priapism	J:225808
	small hippocampus	J:225808
	tremors	J:225808
Scyl2^tm1.2Spel/Scyl2^tm1.2Spel involves: 129S6/SvEvTac * C57BL/6	abnormal behavior	J:225808
	absent gastric milk in neonates	J:225808
	normal craniofacial phenotype	J:225808
	limb grasping	J:225808
	neonatal lethality, incomplete penetrance	J:225808
	postnatal growth retardation	J:225808

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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