Lmbr1l Phenotype Annotations

Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Lmbr1l
limb region 1 like
MGI:1289247

34 phenotypes from 4 alleles in 4 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Lmbr1l^em1Btlr/Lmbr1l^em1Btlr C57BL/6J-Lmbr1l^em1Btlr	abnormal alpha-beta T cell morphology	J:274568
	abnormal B cell differentiation	J:274568
	abnormal bone marrow cell morphology/development	J:274568
	abnormal cytotoxic T cell physiology	J:274568
	abnormal lymphocyte morphology	J:274568
	decreased CD4-positive, alpha-beta T cell number	J:274568
	decreased common lymphocyte progenitor cell number	J:274568
	decreased IgD level	J:274568
	decreased IgG level	J:274568
	decreased IgM level	J:274568
	decreased leukocyte cell number	J:274568
	decreased lymphocyte cell number	J:274568
	decreased monocyte cell number	J:274568
	decreased T cell number	J:274568
	impaired humoral immune response	J:274568
	impaired natural killer cell mediated cytotoxicity	J:274568
	increased hematopoietic cell number	J:274568
	increased IgM level	J:274568
Lmbr1l^m1Btlr/Lmbr1l^m1Btlr C57BL/6J-Lmbr1l^m1Btlr	abnormal CD4-positive T cell differentiation	J:274568
	abnormal CD8-positive, alpha-beta T cell differentiation	J:274568
	abnormal cytotoxic T cell physiology	J:274568
	abnormal T cell differentiation	J:274568
	decreased CD4-positive, alpha-beta T cell number	J:274568
	decreased CD8-positive, alpha-beta T cell number	J:274568
	decreased CD8-positive, naive alpha-beta T cell number	J:274568
	decreased dendritic cell number	J:274568
	decreased IgE level	J:274568
	decreased IgG level	J:274568
	decreased IgM level	J:274568
	decreased NK cell number	J:274568
	decreased NK T cell number	J:274568
	decreased T cell number	J:274568
	impaired humoral immune response	J:274568
	impaired natural killer cell mediated cytotoxicity	J:274568
	increased B-1 B cell number	J:274568
	increased central memory CD8 positive, alpha-beta T cell number	J:274568
	increased effector memory CD4-positive, alpha-beta T cell number	J:274568
	increased macrophage cell number	J:274568
	increased neutrophil cell number	J:274568
Lmbr1l^m2Btlr/Lmbr1l^m2Btlr C57BL/6J-Lmbr1l^m2Btlr	increased central memory CD4-positive, alpha-beta T cell number	J:274857
Lmbr1l^tm1Dgen/Lmbr1l^tm1Dgen involves: 129P2/OlaHsd * C57BL/6	no abnormal phenotype detected	J:101679

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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