Knstrn Phenotype Annotations

Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Knstrn
kinetochore-localized astrin/SPAG5 binding
MGI:1289298

20 phenotypes from 2 alleles in 2 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Knstrn^{tm1b(KOMP)Wtsi}/Knstrn^{tm1b(KOMP)Wtsi} C57BL/6N-Knstrn^{tm1b(KOMP)Wtsi}/Ics	abnormal seminal vesicle morphology	J:211773
	decreased erythrocyte cell number	J:211773
	decreased hematocrit	J:211773
	increased fasting circulating glucose level	J:211773
	increased mean corpuscular hemoglobin	J:211773
	increased mean corpuscular volume	J:211773
	thrombocytopenia	J:211773
	tremors	J:211773
Knstrn^{tm1d(KOMP)Wtsi}/Knstrn^{tm1d(KOMP)Wtsi} involves: C57BL/6J * C57BL/6N	abnormal seminiferous tubule morphology	J:232595
	abnormal Sertoli cell morphology	J:232595
	abnormal spermatogenesis	J:232595
	abnormal spermatogonia proliferation	J:232595
	decreased litter size	J:232595
	decreased male germ cell number	J:232595
	decreased testis weight	J:232595
	increased testis apoptosis	J:232595
	oligozoospermia	J:232595
	reduced fertility	J:232595
	normal reproductive system phenotype	J:232595
	small testis	J:232595

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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