Symbol Name ID |
Hcn4
hyperpolarization-activated, cyclic nucleotide-gated K+ 4 MGI:1298209 |
Allelic Composition Genetic Background |
Annotated Term | Reference |
Gt(ROSA)26Sortm1(DTA)Jpmb/Gt(ROSA)26Sor+ Hcn4tm1(cre/ERT2)Anlu/Hcn4+ involves: 129S/SvEv |
abnormal sinoatrial node morphology | J:186021 |
atrioventricular block | J:186021 | |
cardiac fibrosis | J:186021 | |
decreased heart rate | J:186021 | |
increased heart rate variability | J:186021 | |
irregular heartbeat | J:186021 | |
premature death | J:186021 | |
prolonged PR interval | J:186021 | |
Hcn4tm1Rsei/Hcn4+ B6.Cg-Hcn4tm1Rsei |
decreased heart rate | J:131820 |
Hcn4tm1Rsei/Hcn4tm1Rsei B6.Cg-Hcn4tm1Rsei |
decreased cardiac muscle contractility | J:131820 |
decreased heart rate | J:131820 | |
embryonic lethality during organogenesis, complete penetrance | J:131820 |
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO) |
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last database update 11/12/2024 MGI 6.24 |
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