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Mammalian Phenotype Ontology Annotations
Query Results - Summary
Symbol
Name
ID 		Cnot7
CCR4-NOT transcription complex, subunit 7
MGI:1298230
36 phenotypes from 3 alleles in 3 genetic backgrounds
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Allelic Composition
Genetic Background		 Annotated Term Reference
Cnot7em1(IMPC)Rbrc/Cnot7em1(IMPC)Rbrc
C57BL/6NJcl-Cnot7em1(IMPC)Rbrc/Rbrc 		abnormal behavior J:211773
abnormal heart morphology J:211773
abnormal kidney morphology J:211773
abnormal liver morphology J:211773
abnormal ovary morphology J:211773
abnormal testis morphology J:211773
decreased anxiety-related response J:211773
decreased locomotor activity J:211773
decreased thigmotaxis J:211773
decreased total body fat amount J:211773
enlarged heart J:211773
enlarged kidney J:211773
increased bone mineral content J:211773
increased lean body mass J:211773
increased red blood cell distribution width J:211773
male infertility J:211773
small ovary J:211773
small testis J:211773
Cnot7tm1Jpr/Cnot7tm1Jpr
involves: 129/Sv * C57BL/6 		abnormal gametogenesis J:91598
abnormal male germ cell morphology J:91598
abnormal testis morphology J:91598
decreased male germ cell number J:91598
decreased Sertoli cell number J:91598
decreased testis weight J:91598
increased Leydig cell number J:91598
male infertility J:91598
oligozoospermia J:91598
seminiferous tubule degeneration J:91598
small seminiferous tubules J:91598
Cnot7tm1Tno/Cnot7tm1Tno
involves: 129S4/SvJae * C57BL/6J 		abnormal Sertoli cell morphology J:90439
abnormal sperm flagellum morphology J:90439
abnormal sperm head morphology J:90439
abnormal sperm mitochondrial sheath morphology J:90439
abnormal spermatid morphology J:90439
asthenozoospermia J:90439
increased male germ cell apoptosis J:90439
male infertility J:90439
multinucleated giant male germ cells J:90439
oligozoospermia J:90439
seminiferous tubule degeneration J:90439
small testis J:90439
teratozoospermia J:90439
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
12/10/2024
MGI 6.24 		The Jackson Laboratory